| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-14 |
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| Ligand | BDBM46421 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_754265 (CHEMBL1798952) |
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| IC50 | >100000±n/a nM |
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| Citation |  De Savi, C; Morley, AD; Ting, A; Nash, I; Karabelas, K; Wood, CM; James, M; Norris, SJ; Karoutchi, G; Rankine, N; Hamlin, G; Macfaul, PA; Ryan, D; Baker, SV; Hargreaves, D; Gerhardt, S Selective non zinc binding inhibitors of MMP13. Bioorg Med Chem Lett21:4215-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-14 |
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| Name: | Matrix metalloproteinase-14 |
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| Synonyms: | MMP-14 | MMP-X1 | MMP14 | MMP14_HUMAN | MT-MMP 1 | MT1-MMP | MT1MMP | MTMMP1 | Matrix Metalloproteinase-14 (MMP-14) | Matrix metalloproteinase 14 | Matrix metalloproteinase-14 | Matrix metalloproteinase-14 (MMP14) | Membrane-type matrix metalloproteinase 1 | Membrane-type-1 matrix metalloproteinase |
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| Type: | Protein |
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| Mol. Mass.: | 65900.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50281 |
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| Residue: | 582 |
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| Sequence: | MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE
LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT
SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF
WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF
WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG
NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA
AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
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| BDBM46421 |
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| n/a |
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| Name | BDBM46421 |
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| Synonyms: | 4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide | 4-(4-methylphenoxy)-N-(4-pyridylmethyl)benzamide | 4-(4-methylphenoxy)-N-(pyridin-4-ylmethyl)benzamide | MLS000755676 | SMR000337350 | cid_4358655 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N2O2 |
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| Mol. Mass. | 318.3691 |
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| SMILES | Cc1ccc(Oc2ccc(cc2)C(=O)NCc2ccncc2)cc1 |
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| Structure | 
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