| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
|---|
| Ligand | BDBM50419412 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_785558 (CHEMBL1920205) |
|---|
| IC50 | 50.12±n/a nM |
|---|
| Citation |  Allan, AC; Billinton, A; Brown, SH; Chowdhury, A; Eatherton, AJ; Fieldhouse, C; Giblin, GM; Goldsmith, P; Hall, A; Hurst, DN; Naylor, A; Rawlings, DA; Sime, M; Scoccitti, T; Theobald, PJ Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists. Bioorg Med Chem Lett21:4343-8 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP1 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP1 subtype |
|---|
| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41834.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34995 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
|
|
|
|---|
| BDBM50419412 |
|---|
| n/a |
|---|
| Name | BDBM50419412 |
|---|
| Synonyms: | CHEMBL1915013 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H15ClN2O3 |
|---|
| Mol. Mass. | 330.766 |
|---|
| SMILES | Cc1cc(nn1Cc1cc(Cl)cc2cc(oc12)C1CC1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
