| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide S receptor |
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| Ligand | BDBM50417462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1276615 (CHEMBL3088900) |
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| IC50 | 26±n/a nM |
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| Citation |  Patnaik, S; Marugan, JJ; Liu, K; Zheng, W; Southall, N; Dehdashti, SJ; Thorsell, A; Heilig, M; Bell, L; Zook, M; Eskay, B; Brimacombe, KR; Austin, CP Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor. J Med Chem56:9045-56 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide S receptor |
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| Name: | Neuropeptide S receptor |
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| Synonyms: | GPR154 | GPRA | NPSR1 | NPSR1_HUMAN | PGR14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42692.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1276607 |
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| Residue: | 371 |
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| Sequence: | MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
VFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLV
CRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIP
TLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK
SKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFN
LLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERH
EMQILSKPEFI
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| BDBM50417462 |
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| n/a |
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| Name | BDBM50417462 |
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| Synonyms: | CHEMBL469696 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25N3O3 |
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| Mol. Mass. | 427.495 |
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| SMILES | O=C(NCc1ccccc1)N1CCN2C(C1)C(OC2=O)(c1ccccc1)c1ccccc1 |
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| Structure | 
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