| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50002601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_352667 (CHEMBL862146) |
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| EC50 | 1585±n/a nM |
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| Citation |  Uehling, DE; Shearer, BG; Donaldson, KH; Chao, EY; Deaton, DN; Adkison, KK; Brown, KK; Cariello, NF; Faison, WL; Lancaster, ME; Lin, J; Hart, R; Milliken, TO; Paulik, MA; Sherman, BW; Sugg, EE; Cowan, C Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists. J Med Chem49:2758-71 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50002601 |
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| n/a |
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| Name | BDBM50002601 |
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| Synonyms: | CHEMBL383511 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25ClN2O3 |
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| Mol. Mass. | 424.92 |
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| SMILES | C[C@H](CNc1cccc(c1)-c1ccc(cc1)C(O)=O)NC[C@H](O)c1cccc(Cl)c1 |
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| Structure | 
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