| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50002598 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_352669 (CHEMBL862149) |
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| EC50 | <794±n/a nM |
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| Citation |  Uehling, DE; Shearer, BG; Donaldson, KH; Chao, EY; Deaton, DN; Adkison, KK; Brown, KK; Cariello, NF; Faison, WL; Lancaster, ME; Lin, J; Hart, R; Milliken, TO; Paulik, MA; Sherman, BW; Sugg, EE; Cowan, C Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists. J Med Chem49:2758-71 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51338.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08588 |
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| Residue: | 477 |
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| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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| BDBM50002598 |
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| n/a |
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| Name | BDBM50002598 |
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| Synonyms: | CHEMBL152535 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClNO4 |
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| Mol. Mass. | 362.828 |
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| SMILES | C[C@H](Cc1ccc(OCC([O-])=O)cc1)NC[C@H](O)c1cccc(Cl)c1 |
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| Structure | 
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