| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17A |
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| Ligand | BDBM50166267 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1575377 (CHEMBL3802095) |
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| IC50 | 460±n/a nM |
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| Citation |  Jung, ME; Byun, BJ; Kim, HM; Lee, JY; Park, JH; Lee, N; Son, YH; Choi, SU; Yang, KM; Kim, SJ; Lee, K; Kim, YC; Choi, G Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening. Bioorg Med Chem Lett26:2719-23 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17A |
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| Name: | Serine/threonine-protein kinase 17A |
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| Synonyms: | DRAK1 | ST17A_HUMAN | STK17A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46544.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_109255245 |
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| Residue: | 414 |
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| Sequence: | MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYS
LCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPW
VINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTR
DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPI
SMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRT
LLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSE
TKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
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| BDBM50166267 |
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| n/a |
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| Name | BDBM50166267 |
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| Synonyms: | CHEMBL3799218 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17ClN4O4 |
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| Mol. Mass. | 460.869 |
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| SMILES | O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(NC(=O)COc3cccc(Cl)c3)cc12 |
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| Structure | 
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