Compile Data Set for Download or QSAR

Found 459 hits with Last Name = 'choi' and Initial = 'su'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 17B (Homo sapiens (Human))	BDBM50166121 (CHEMBL3797480) Show SMILES CCCCC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C21H20N4O3/c1-2-3-8-17(26)22-12-9-10-16-14(11-12)18(21(27)24-16)20-19(25-28)13-6-4-5-7-15(13)23-20/h4-7,9-11,23,28H,2-3,8H2,1H3,(H,22,26)(H,24,27)/b20-18-,25-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Competitive inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by Lineweaver-Burk plot analysis in presence of...				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384024 (CHEMBL2032280 | CHEMBL2079349) Show SMILES Cc1c(O)ccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-18(28)3-2-17-19(12)29-21(26-17)16-8-13(9-24-20(16)22)14-10-25-27(11-14)15-4-6-23-7-5-15/h2-3,8-11,15,23,28H,4-7H2,1H3,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50384038 (CHEMBL2032155) Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238943 (US9403831, 32) Show SMILES OCCn1cc(cn1)-c1cnc(nc1)N1CCOC(Cn2nnc3ncc(nc23)-c2ccc(F)c(c2)C#N)C1 Show InChI InChI=1S/C25H22FN11O2/c26-21-2-1-16(7-17(21)8-27)22-12-28-23-24(32-22)37(34-33-23)15-20-14-35(4-6-39-20)25-29-9-18(10-30-25)19-11-31-36(13-19)3-5-38/h1-2,7,9-13,20,38H,3-6,14-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384038 (CHEMBL2032155) Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50205347 (CHEMBL3947950) Show SMILES CC1(C)C[C@@H](N(C1)c1ccn2ncc(NC(=O)c3cnccn3)c2n1)c1cc(F)ccc1F |r| Show InChI InChI=1S/C23H21F2N7O/c1-23(2)10-19(15-9-14(24)3-4-16(15)25)31(13-23)20-5-8-32-21(30-20)17(12-28-32)29-22(33)18-11-26-6-7-27-18/h3-9,11-12,19H,10,13H2,1-2H3,(H,29,33)/t19-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University Curated by ChEMBL					Assay Description Inhibition of TrkA (unknown origin) by ELISA				Bioorg Med Chem 25: 389-396 (2017) Article DOI: 10.1016/j.bmc.2016.11.005 BindingDB Entry DOI: 10.7270/Q2JM2CNM
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193503 (US9199944, 85) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C30H39ClN8O4/c1-21(41)37-12-14-39(15-13-37)23-4-6-25(27(18-23)42-2)33-29-24(31)20-32-30(35-29)34-26-7-5-22(19-28(26)43-3)38-10-8-36(9-11-38)16-17-40/h4-7,18-20,40H,8-17H2,1-3H3,(H2,32,33,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193475 (US9199944, 57) Show SMILES CCNC(=O)N1CCN(CC1)c1ccc(Nc2nc(Nc3ccc(cc3OC)N3CCN(CC3)C(C)=O)ncc2C(F)(F)F)c(OC)c1 Show InChI InChI=1S/C32H40F3N9O4/c1-5-36-31(46)44-16-14-43(15-17-44)22-6-8-25(27(18-22)47-3)38-29-24(32(33,34)35)20-37-30(40-29)39-26-9-7-23(19-28(26)48-4)42-12-10-41(11-13-42)21(2)45/h6-9,18-20H,5,10-17H2,1-4H3,(H,36,46)(H2,37,38,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193476 (US9199944, 58) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(=O)CO)n1)C(F)(F)F)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C31H37F3N8O5/c1-20(44)39-8-10-40(11-9-39)22-5-7-25(27(17-22)47-3)37-30-35-18-23(31(32,33)34)29(38-30)36-24-6-4-21(16-26(24)46-2)41-12-14-42(15-13-41)28(45)19-43/h4-7,16-18,43H,8-15,19H2,1-3H3,(H2,35,36,37,38)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238925 (US9403831, 6) Show SMILES Cn1cc(cn1)-c1cnc2nnn(C[C@@H]3CN(CCO3)c3ncc(cn3)-c3cnn(c3)C3CCNCC3)c2n1 |r| Show InChI InChI=1S/C25H29N13O/c1-35-13-19(11-30-35)22-12-27-23-24(32-22)38(34-33-23)16-21-15-36(6-7-39-21)25-28-8-17(9-29-25)18-10-31-37(14-18)20-2-4-26-5-3-20/h8-14,20-21,26H,2-7,15-16H2,1H3/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238935 (US9403831, 20) Show SMILES CN1CCC(CC1)c1cnc(nc1)N1CCO[C@H](Cn2nnc3ncc(nc23)-c2cnn(C)c2)C1 |r| Show InChI InChI=1S/C23H29N11O/c1-31-5-3-16(4-6-31)17-9-25-23(26-10-17)33-7-8-35-19(14-33)15-34-22-21(29-30-34)24-12-20(28-22)18-11-27-32(2)13-18/h9-13,16,19H,3-8,14-15H2,1-2H3/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238928 (US9403831, 24) Show SMILES OCCN1CCC(=CC1)c1cnc(nc1)N1CCO[C@H](Cn2nnc3ncc(nc23)-c2cccc(c2)C#N)C1 |r,c:6| Show InChI InChI=1S/C27H28N10O2/c28-13-19-2-1-3-21(12-19)24-16-29-25-26(32-24)37(34-33-25)18-23-17-36(9-11-39-23)27-30-14-22(15-31-27)20-4-6-35(7-5-20)8-10-38/h1-4,12,14-16,23,38H,5-11,17-18H2/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238964 (US9403831, 29) Show SMILES Cn1cc(cn1)-c1cnc(nc1)N1CCO[C@H](Cn2nnc3ncc(nc23)-c2ccc(F)c(c2)C#N)C1 |r| Show InChI InChI=1S/C24H20FN11O/c1-34-12-18(10-30-34)17-8-28-24(29-9-17)35-4-5-37-19(13-35)14-36-23-22(32-33-36)27-11-21(31-23)15-2-3-20(25)16(6-15)7-26/h2-3,6,8-12,19H,4-5,13-14H2,1H3/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238944 (US9403831, 30) Show SMILES Fc1ccc(cc1C#N)-c1cnc2nnn(C[C@@H]3CN(CCO3)c3ncc(cn3)C3=CCNCC3)c2n1 |r,t:32| Show InChI InChI=1S/C25H23FN10O/c26-21-2-1-17(9-18(21)10-27)22-13-29-23-24(32-22)36(34-33-23)15-20-14-35(7-8-37-20)25-30-11-19(12-31-25)16-3-5-28-6-4-16/h1-3,9,11-13,20,28H,4-8,14-15H2/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238942 (US9403831, 31) Show SMILES OCCn1cc(cn1)-c1cnc(nc1)N1CCO[C@H](Cn2nnc3ncc(nc23)-c2cccc(c2)C#N)C1 |r| Show InChI InChI=1S/C25H23N11O2/c26-9-17-2-1-3-18(8-17)22-13-27-23-24(31-22)36(33-32-23)16-21-15-34(5-7-38-21)25-28-10-19(11-29-25)20-12-30-35(14-20)4-6-37/h1-3,8,10-14,21,37H,4-7,15-16H2/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238951 (US9403831, 36) Show SMILES Cn1cc(cn1)-c1cnc2nnn(CC3CCCN(C3)c3ncc(cn3)-c3cnn(CCO)c3)c2n1 Show InChI InChI=1S/C23H26N12O/c1-32-14-19(10-27-32)20-11-24-21-22(29-20)35(31-30-21)13-16-3-2-4-33(12-16)23-25-7-17(8-26-23)18-9-28-34(15-18)5-6-36/h7-11,14-16,36H,2-6,12-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238952 (US9403831, 37) Show SMILES Cn1cc(cn1)-c1cnc2nnn(CC3CCCN(C3)c3ncc(cn3)-c3cnn(c3)C3CCNCC3)c2n1 Show InChI InChI=1S/C26H31N13/c1-36-16-21(12-31-36)23-13-28-24-25(33-23)39(35-34-24)15-18-3-2-8-37(14-18)26-29-9-19(10-30-26)20-11-32-38(17-20)22-4-6-27-7-5-22/h9-13,16-18,22,27H,2-8,14-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238946 (US9403831, 39) Show SMILES CN1CCN(Cc2ccc(cc2F)-c2cnc(nc2)N2CCOC(Cn3nnc4ncc(nc34)-c3ccc(F)c(c3)C#N)C2)CC1 Show InChI InChI=1S/C32H31F2N11O/c1-42-6-8-43(9-7-42)18-23-3-2-21(13-28(23)34)25-15-37-32(38-16-25)44-10-11-46-26(19-44)20-45-31-30(40-41-45)36-17-29(39-31)22-4-5-27(33)24(12-22)14-35/h2-5,12-13,15-17,26H,6-11,18-20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50384004 (CHEMBL2032276) Show SMILES Cc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-6-19-17(8-18(12)28)26-21(29-19)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358291 (CHEMBL1922406) Show SMILES OCCn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C20H17N7O2/c28-9-8-26-12-14(11-22-26)17-4-5-18-23-24-19(27(18)25-17)10-13-2-1-3-16-15(13)6-7-21-20(16)29/h1-7,11-12,28H,8-10H2,(H,21,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238947 (US9403831, 40) Show SMILES CN1CCN(Cc2ccc(cc2F)-c2cnc(nc2)N2CCOC(Cn3nnc4ncc(nc34)-c3cnn(C)c3)C2)CC1 Show InChI InChI=1S/C29H33FN12O/c1-38-5-7-40(8-6-38)17-21-4-3-20(11-25(21)30)22-12-32-29(33-13-22)41-9-10-43-24(18-41)19-42-28-27(36-37-42)31-15-26(35-28)23-14-34-39(2)16-23/h3-4,11-16,24H,5-10,17-19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50030308 (CHEMBL3335781) Show SMILES OCCN1CCC(=CC1)c1cnc(nc1)N1CCO[C@H](Cn2nc(ccc2=O)-c2cccc(c2)C#N)C1 |r,c:6| Show InChI InChI=1S/C27H29N7O3/c28-15-20-2-1-3-22(14-20)25-4-5-26(36)34(31-25)19-24-18-33(11-13-37-24)27-29-16-23(17-30-27)21-6-8-32(9-7-21)10-12-35/h1-6,14,16-17,24,35H,7-13,18-19H2/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by HTRF assay				Bioorg Med Chem Lett 24: 5093-7 (2014) Article DOI: 10.1016/j.bmcl.2014.08.067 BindingDB Entry DOI: 10.7270/Q2T43VQB
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50030291 (CHEMBL3335768) Show SMILES OCCN1CCC(CC1)n1cc(cn1)-c1cnc(nc1)N1CCO[C@H](Cn2nc(ccc2=O)-c2cc(F)c(F)c(F)c2)C1 |r| Show InChI InChI=1S/C29H31F3N8O3/c30-24-11-19(12-25(31)28(24)32)26-1-2-27(42)40(36-26)18-23-17-38(8-10-43-23)29-33-13-20(14-34-29)21-15-35-39(16-21)22-3-5-37(6-4-22)7-9-41/h1-2,11-16,22-23,41H,3-10,17-18H2/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by HTRF assay				Bioorg Med Chem Lett 24: 5093-7 (2014) Article DOI: 10.1016/j.bmcl.2014.08.067 BindingDB Entry DOI: 10.7270/Q2T43VQB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17B (Homo sapiens (Human))	BDBM50166121 (CHEMBL3797480) Show SMILES CCCCC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C21H20N4O3/c1-2-3-8-17(26)22-12-9-10-16-14(11-12)18(21(27)24-16)20-19(25-28)13-6-4-5-7-15(13)23-20/h4-7,9-11,23,28H,2-3,8H2,1H3,(H,22,26)(H,24,27)/b20-18-,25-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assay				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358289 (CHEMBL1922405) Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3ccccc3)cccc12 Show InChI InChI=1S/C21H15N5O/c27-21-17-8-4-7-15(16(17)11-12-22-21)13-20-24-23-19-10-9-18(25-26(19)20)14-5-2-1-3-6-14/h1-12H,13H2,(H,22,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358301 (CHEMBL1922416) Show SMILES Fc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H14FN5O/c22-15-5-1-4-14(11-15)18-7-8-19-24-25-20(27(19)26-18)12-13-3-2-6-17-16(13)9-10-23-21(17)28/h1-11H,12H2,(H,23,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358303 (CHEMBL1922418) Show SMILES O=c1[nH]ccc2c(Cc3nnc4ccc(nn34)-c3cccc(c3)C#N)cccc12 Show InChI InChI=1S/C22H14N6O/c23-13-14-3-1-5-16(11-14)19-7-8-20-25-26-21(28(20)27-19)12-15-4-2-6-18-17(15)9-10-24-22(18)29/h1-11H,12H2,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358304 (CHEMBL1922419) Show SMILES Oc1cccc(c1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C21H15N5O2/c27-15-5-1-4-14(11-15)18-7-8-19-23-24-20(26(19)25-18)12-13-3-2-6-17-16(13)9-10-22-21(17)28/h1-11,27H,12H2,(H,22,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384027 (CHEMBL2032277) Show SMILES Cc1cc2oc(nc2c(C)c1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H24N6O2/c1-12-7-18-19(13(2)20(12)29)27-22(30-18)17-8-14(9-25-21(17)23)15-10-26-28(11-15)16-3-5-24-6-4-16/h7-11,16,24,29H,3-6H2,1-2H3,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50142026 (3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...) Show SMILES Cn1cc(\C=C2/C(=O)Nc3cccnc23)c2ccccc12 Show InChI InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University Curated by ChEMBL					Assay Description Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...				Bioorg Med Chem 25: 389-396 (2017) Article DOI: 10.1016/j.bmc.2016.11.005 BindingDB Entry DOI: 10.7270/Q2JM2CNM
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193475 (US9199944, 57) Show SMILES CCNC(=O)N1CCN(CC1)c1ccc(Nc2nc(Nc3ccc(cc3OC)N3CCN(CC3)C(C)=O)ncc2C(F)(F)F)c(OC)c1 Show InChI InChI=1S/C32H40F3N9O4/c1-5-36-31(46)44-16-14-43(15-17-44)22-6-8-25(27(18-22)47-3)38-29-24(32(33,34)35)20-37-30(40-29)39-26-9-7-23(19-28(26)48-4)42-12-10-41(11-13-42)21(2)45/h6-9,18-20H,5,10-17H2,1-4H3,(H,36,46)(H2,37,38,39,40)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193481 (US9199944, 63) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)C(F)(F)F)N1CCNCC1 Show InChI InChI=1S/C29H35F3N8O3/c1-19(41)38-12-14-40(15-13-38)21-4-6-23(25(17-21)42-2)35-27-22(29(30,31)32)18-34-28(37-27)36-24-7-5-20(16-26(24)43-3)39-10-8-33-9-11-39/h4-7,16-18,33H,8-15H2,1-3H3,(H2,34,35,36,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193486 (US9199944, 68) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)C(F)(F)F)N1CCN(CCO)CC1 Show InChI InChI=1S/C31H39F3N8O4/c1-21(44)40-12-14-42(15-13-40)23-4-6-25(27(18-23)45-2)36-29-24(31(32,33)34)20-35-30(38-29)37-26-7-5-22(19-28(26)46-3)41-10-8-39(9-11-41)16-17-43/h4-7,18-20,43H,8-17H2,1-3H3,(H2,35,36,37,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193487 (US9199944, 69) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCNCC2)n1)C(F)(F)F)N1CCNCC1 Show InChI InChI=1S/C27H33F3N8O2/c1-39-23-15-18(37-11-7-31-8-12-37)3-5-21(23)34-25-20(27(28,29)30)17-33-26(36-25)35-22-6-4-19(16-24(22)40-2)38-13-9-32-10-14-38/h3-6,15-17,31-32H,7-14H2,1-2H3,(H2,33,34,35,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193490 (US9199944, 72) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(=O)CO)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO Show InChI InChI=1S/C31H37F3N8O6/c1-47-25-15-20(39-7-11-41(12-8-39)27(45)18-43)3-5-23(25)36-29-22(31(32,33)34)17-35-30(38-29)37-24-6-4-21(16-26(24)48-2)40-9-13-42(14-10-40)28(46)19-44/h3-6,15-17,43-44H,7-14,18-19H2,1-2H3,(H2,35,36,37,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM193495 (US9199944, 77) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccc(cc2OC)N2CCNCC2)n1)N1CCNCC1 Show InChI InChI=1S/C26H33ClN8O2/c1-36-23-15-18(34-11-7-28-8-12-34)3-5-21(23)31-25-20(27)17-30-26(33-25)32-22-6-4-19(16-24(22)37-2)35-13-9-29-10-14-35/h3-6,15-17,28-29H,7-14H2,1-2H3,(H2,30,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193477 (US9199944, 59) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(C)CC2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C30H37F3N8O3/c1-20(42)39-13-15-41(16-14-39)22-6-8-25(27(18-22)44-4)36-29-34-19-23(30(31,32)33)28(37-29)35-24-7-5-21(17-26(24)43-3)40-11-9-38(2)10-12-40/h5-8,17-19H,9-16H2,1-4H3,(H2,34,35,36,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193478 (US9199944, 60) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)S(C)(=O)=O)n1)C(F)(F)F)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C30H37F3N8O5S/c1-20(42)38-9-11-39(12-10-38)21-6-8-25(27(18-21)46-3)36-29-34-19-23(30(31,32)33)28(37-29)35-24-7-5-22(17-26(24)45-2)40-13-15-41(16-14-40)47(4,43)44/h5-8,17-19H,9-16H2,1-4H3,(H2,34,35,36,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193481 (US9199944, 63) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)C(F)(F)F)N1CCNCC1 Show InChI InChI=1S/C29H35F3N8O3/c1-19(41)38-12-14-40(15-13-38)21-4-6-23(25(17-21)42-2)35-27-22(29(30,31)32)18-34-28(37-27)36-24-7-5-20(16-26(24)43-3)39-10-8-33-9-11-39/h4-7,16-18,33H,8-15H2,1-3H3,(H2,34,35,36,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193483 (US9199944, 65) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)C(F)(F)F)N1CCN(CC1)C(=O)CO Show InChI InChI=1S/C31H37F3N8O5/c1-20(44)39-8-10-40(11-9-39)21-4-6-24(26(16-21)46-2)36-29-23(31(32,33)34)18-35-30(38-29)37-25-7-5-22(17-27(25)47-3)41-12-14-42(15-13-41)28(45)19-43/h4-7,16-18,43H,8-15,19H2,1-3H3,(H2,35,36,37,38)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human))	BDBM193484 (US9199944, 66) Show SMILES COc1cc(ccc1Nc1ncc(c(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)n1)C(F)(F)F)N1CCN(C)CC1 Show InChI InChI=1S/C30H37F3N8O3/c1-20(42)39-13-15-41(16-14-39)22-5-7-24(26(17-22)43-3)35-28-23(30(31,32)33)19-34-29(37-28)36-25-8-6-21(18-27(25)44-4)40-11-9-38(2)10-12-40/h5-8,17-19H,9-16H2,1-4H3,(H2,34,35,36,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...				US Patent US9199944 (2015) BindingDB Entry DOI: 10.7270/Q2J96558
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238937 (US9403831, 9) Show SMILES Cn1cc(cn1)-c1cnc2nnn(C[C@@H]3CN(CCO3)c3ncc(cn3)C3=CCOCC3)c2n1 |r,t:29| Show InChI InChI=1S/C22H24N10O2/c1-30-12-17(10-26-30)19-11-23-20-21(27-19)32(29-28-20)14-18-13-31(4-7-34-18)22-24-8-16(9-25-22)15-2-5-33-6-3-15/h2,8-12,18H,3-7,13-14H2,1H3/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238939 (US9403831, 11) Show SMILES Cn1cc(cn1)-c1cnc2nnn(C[C@@H]3CN(CCO3)c3ncc(cn3)-c3cnn(CCO)c3)c2n1 |r| Show InChI InChI=1S/C22H24N12O2/c1-31-11-17(9-26-31)19-10-23-20-21(28-19)34(30-29-20)14-18-13-32(3-5-36-18)22-24-6-15(7-25-22)16-8-27-33(12-16)2-4-35/h6-12,18,35H,2-5,13-14H2,1H3/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238953 (US9403831, 17) Show SMILES CN1CCN(Cc2ccc(cc2)-c2cnc(nc2)N2CCO[C@H](Cn3nnc4ncc(nc34)-c3cnn(C)c3)C2)CC1 |r| Show InChI InChI=1S/C29H34N12O/c1-37-7-9-39(10-8-37)17-21-3-5-22(6-4-21)23-13-31-29(32-14-23)40-11-12-42-25(19-40)20-41-28-27(35-36-41)30-16-26(34-28)24-15-33-38(2)18-24/h3-6,13-16,18,25H,7-12,17,19-20H2,1-2H3/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238959 (US9403831, 23 | US9403831, 25) Show SMILES CN1CCC(=CC1)c1cnc(nc1)N1CCO[C@H](Cn2nnc3ncc(nc23)-c2cccc(c2)C#N)C1 |r,c:4| Show InChI InChI=1S/C26H26N10O/c1-34-7-5-19(6-8-34)21-13-29-26(30-14-21)35-9-10-37-22(16-35)17-36-25-24(32-33-36)28-15-23(31-25)20-4-2-3-18(11-20)12-27/h2-5,11,13-15,22H,6-10,16-17H2,1H3/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238949 (US9403831, 33) Show SMILES Cn1cc(cn1)-c1cnc2nnn(CC3CCCN(C3)c3ncc(cn3)C3=CCNCC3)c2n1 |t:29| Show InChI InChI=1S/C23H27N11/c1-32-15-19(11-28-32)20-12-25-21-22(29-20)34(31-30-21)14-16-3-2-8-33(13-16)23-26-9-18(10-27-23)17-4-6-24-7-5-17/h4,9-12,15-16,24H,2-3,5-8,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238948 (US9403831, 34) Show SMILES CN1CCC(=CC1)c1cnc(nc1)N1CCCC(Cn2nnc3ncc(nc23)-c2cnn(C)c2)C1 |c:4| Show InChI InChI=1S/C24H29N11/c1-32-8-5-18(6-9-32)19-10-26-24(27-11-19)34-7-3-4-17(14-34)15-35-23-22(30-31-35)25-13-21(29-23)20-12-28-33(2)16-20/h5,10-13,16-17H,3-4,6-9,14-15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238950 (US9403831, 35) Show SMILES Cn1cc(cn1)-c1cnc2nnn(CC3CCCN(C3)c3ncc(cn3)C3=CCN(CCO)CC3)c2n1 |t:29| Show InChI InChI=1S/C25H31N11O/c1-33-17-21(13-29-33)22-14-26-23-24(30-22)36(32-31-23)16-18-3-2-6-35(15-18)25-27-11-20(12-28-25)19-4-7-34(8-5-19)9-10-37/h4,11-14,17-18,37H,2-3,5-10,15-16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM238965 (US9403831, 38) Show SMILES OCCN1CCC(=CC1)c1cnc(nc1)N1CCOC(Cn2nnc3ncc(nc23)-c2ccc(F)c(c2)C#N)C1 |c:6| Show InChI InChI=1S/C27H27FN10O2/c28-23-2-1-19(11-20(23)12-29)24-15-30-25-26(33-24)38(35-34-25)17-22-16-37(8-10-40-22)27-31-13-21(14-32-27)18-3-5-36(6-4-18)7-9-39/h1-3,11,13-15,22,39H,4-10,16-17H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. US Patent					Assay Description The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...				US Patent US9403831 (2016) BindingDB Entry DOI: 10.7270/Q2TD9W7H
					More data for this Ligand-Target Pair

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