Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50016867 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1588482 (CHEMBL3826765) |
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IC50 | 781±n/a nM |
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Citation | Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW [Dmt(1)]DALDA analogues modified with tyrosine analogues at position 1. Bioorg Med Chem Lett26:3629-31 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 40577.25 |
Organism: | MOUSE |
Description: | P32300 |
Residue: | 372 |
Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
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BDBM50016867 |
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n/a |
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Name | BDBM50016867 |
Synonyms: | (S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoylamino}-3-phenyl-propionylamino)-hexanoic acid amide | 6-amino-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-(2S)-hexanamide | CHEMBL60444 |
Type | Small organic molecule |
Emp. Form. | C30H45N9O5 |
Mol. Mass. | 611.7356 |
SMILES | NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O |
Structure |
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