| Reaction Details |
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 | Report a problem with these data |
| Target | Uncharacterized protein YOR062C |
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| Ligand | BDBM166703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Tyrosinase Inhibition Assay |
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| pH | 6.8±n/a |
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| IC50 | 5.35e+3± 1.5e+2 nM |
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| Comments | extracted |
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| Citation |  Xie, W; Zhang, J; Ma, X; Yang, W; Zhou, Y; Tang, X; Zou, Y; Li, H; He, J; Xie, S; Zhao, Y; Liu, F Synthesis and biological evaluation of kojic acid derivatives containing 1,2,4-triazole as potent tyrosinase inhibitors. Chem Biol Drug Des86:1087-92 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Uncharacterized protein YOR062C |
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| Name: | Uncharacterized protein YOR062C |
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| Synonyms: | Tyrosinase | YO062_YEAST |
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| Type: | Protein |
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| Mol. Mass.: | 31886.70 |
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| Organism: | Agaricus bisporus (Mushroom) |
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| Description: | O00024 |
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| Residue: | 268 |
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| Sequence: | MTSLDDSVLTKKNIALLDNATNYIRPAIDYFHFKFNYDSLDVSTTWRLLLKMRKHKLLRL
PSCSSENEFDYSIYMARLYHCIWRRWSIKHFNLDEYKIDPLSINWNKEIDVTVLYGPDLV
GIHEREQPTPTDFPMGNIKEQGKQLLDVRKEGSASSLLKKGSVFYSKGKWLSQRSISFDD
TVRRRDIDKRGRFRESCVLINDVEQFQNYSIVWDESRHRYRRQALPDTYDYEHLYPNGDE
TPRNTPHDNIIIHQNLHSITEGSYIYIK
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| BDBM166703 |
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| n/a |
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| Name | BDBM166703 |
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| Synonyms: | 5-(2-chlorophenyl)-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto]-4-amino-1,2,4-triazole (6k) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11ClN4O3S |
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| Mol. Mass. | 350.78 |
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| SMILES | Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1Cl |
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| Structure | 
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