| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM50537599 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assays |
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| IC50 | 6118±n/a nM |
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| Citation |  Arancio, O; Watterson, DM; Pelletier, JC; Roy, SM MAP kinase modulators and uses thereof US Patent US11149020 Publication Date 10/19/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47356.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48730 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM50537599 |
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| n/a |
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| Name | BDBM50537599 |
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| Synonyms: | CHEMBL4648060 | US11149020, Compound 2 (MW-108) |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4 |
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| Mol. Mass. | 326.3944 |
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| SMILES | CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 |
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| Structure | 
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