| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
|---|
| Ligand | BDBM50513404 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1853391 (CHEMBL4354015) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Hogendorf, AS; Hogendorf, A; Kurczab, R; Kalinowska-T?u?cik, J; Popik, P; Nikiforuk, A; Krawczyk, M; Sata?a, G; Lenda, T; Knutelska, J; Bugno, R; Staro?, J; Pietru?, W; Mat?oka, M; Dubiel, K; Moszczy?ski-P?tkowski, R; Pieczykolan, J; Wieczorek, M; Pilarski, B; Zajdel, P; Bojarski, AJ 2-Aminoimidazole-based antagonists of the 5-HT Eur J Med Chem179:1-15 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 7 |
|---|
| Name: | 5-hydroxytryptamine receptor 7 |
|---|
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 53573.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34969 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
|
|
|
|---|
| BDBM50513404 |
|---|
| n/a |
|---|
| Name | BDBM50513404 |
|---|
| Synonyms: | CHEMBL4451666 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17FN4O4S |
|---|
| Mol. Mass. | 428.437 |
|---|
| SMILES | COc1ccc2n(cc(-c3cnc(NC(C)=O)[nH]3)c2c1)S(=O)(=O)c1cccc(F)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
