| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50408756 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86733 (CHEMBL693458) |
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| EC50 | 128±n/a nM |
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| Citation |  Sasse, A; Stark, H; Reidemeister, S; Hüls, A; Elz, S; Ligneau, X; Ganellin, CR; Schwartz, JC; Schunack, W Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity. J Med Chem42:4269-74 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50408756 |
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| n/a |
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| Name | BDBM50408756 |
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| Synonyms: | CHEMBL2145444 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H20N2O |
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| Mol. Mass. | 196.2893 |
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| SMILES | CC(C)CCOCCCc1cnc[nH]1 |
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| Structure | 
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