| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50541996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1985762 (CHEMBL4619168) |
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| IC50 | 246±n/a nM |
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| Citation |  Mufti, F; Jung, YH; Giancotti, LA; Yu, J; Chen, Z; Phung, NB; Jacobson, KA; Salvemini, D P2Y ACS Med Chem Lett11:1281-1286 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | G-protein coupled receptor 105 | Gpr105 | P2Y14 | P2Y14_MOUSE | P2ry14 | UDP-glucose receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38883.93 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_745158 |
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| Residue: | 338 |
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| Sequence: | MNNSTTTDPPNQPCSWNTLITKQIIPVLYGMVFITGLLLNGISGWIFFYVPSSKSFIIYL
KNIVVADFLMGLTFPFKVLGDSGLGPWQVNVFVCRVSAVIFYVNMYVSIVFFGLISFDRY
YKIVKPLLTSIVQSVNYSKLLSVLVWMLMLLLAVPNIILTNQGVKEVTKIQCMELKNELG
RKWHKASNYIFVSIFWVVFLLLIVFYTAITRKIFKSHLKSRKNSTSVKRKSSRNIFSIVL
VFVVCFVPYHIARIPYTKSQTEGHYSCRTKETLLYAKEFTLLLSAANVCLDPIIYFFLCQ
PFREVLNKKLHMSLKVQNDLEVSKTKRENAIHESTDTL
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| BDBM50541996 |
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| n/a |
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| Name | BDBM50541996 |
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| Synonyms: | CHEMBL4633982 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H23F3N4O2 |
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| Mol. Mass. | 492.4923 |
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| SMILES | OC(=O)c1cc(cc(c1)-c1ccc(cc1)C1CCNCC1)-c1cn(nn1)-c1ccc(cc1)C(F)(F)F |
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| Structure | 
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