| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate carboxypeptidase 2 |
|---|
| Ligand | BDBM50106574 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_141138 (CHEMBL749038) |
|---|
| IC50 | 508±n/a nM |
|---|
| Citation |  Jackson, PF; Tays, KL; Maclin, KM; Ko, YS; Li, W; Vitharana, D; Tsukamoto, T; Stoermer, D; Lu, XC; Wozniak, K; Slusher, BS Design and pharmacological activity of phosphinic acid based NAALADase inhibitors. J Med Chem44:4170-5 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate carboxypeptidase 2 |
|---|
| Name: | Glutamate carboxypeptidase 2 |
|---|
| Synonyms: | FOLH1_RAT | Folh1 | Glutamate carboxypeptidase II | Naalad1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 84547.28 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_68365 |
|---|
| Residue: | 752 |
|---|
| Sequence: | MWNAQQDSDSAEALGRRQRWFCAGTLVLAFTGTFIIGFLFGWFIKPSNDSTSSVSYPGMK
KAFLQELKAENIKKFLYNFTRTPHLAGTQHNFELAKQIHAQWKEFGLDLVELSDYDVLLS
YPNKTHPNYISIINEDGNEIFKTSLAELSPPGYENISDVVPPYSAFSPQGTPEGDLVYVN
YARTEDFFKLERVMKINCSGKIVIARYGQVFRGNKVKNAQLAGAKGIILYSDPADYFVPG
VKSYPDGWNLPGGGVQRGNVLNLNGAGDPLTPGYPANEYAYRHEFTEAVGLPSIPVHPIG
YDDAQKLLEHMGGSAPPDSSWKGGLKVPYNVGPGFAGNFSKQKVKLHIHSYNKVTRIYNV
IGTLKGAVEPDRYVILGGHRDAWVFGGIDPQSGAAVVHEIVRTFGTLKKKGWRPRRTILF
ASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMHSLVYNLT
KELPSPDEGFEGKSLYDSWKEKSPSTEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYT
KNWKNNKVSSYPLYHSVYETYELVEKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQ
SYAVALKKHAETIYNISMNHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQDLDKSNP
ILLRILNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDINNK
VDTSKAWREVKRQISIAAFTVQAAAETLREVD
|
|
|
|---|
| BDBM50106574 |
|---|
| n/a |
|---|
| Name | BDBM50106574 |
|---|
| Synonyms: | 2-(3-Hydroxy-benzyl)-3-phosphono-propionic acid | CHEMBL334532 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H13O6P |
|---|
| Mol. Mass. | 260.1804 |
|---|
| SMILES | OC(=O)C(Cc1cccc(O)c1)CP(O)(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
