Compile Data Set for Download or QSAR

Found 134 hits with Last Name = 'ko' and Initial = 'ys'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against glutamate carboxypeptidase II (GCP II) using N-acetyl-L-aspartyl-[3H]-L-glutamate as a substrate				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50109593 (2-Benzyl-3-mercapto-propionic acid | 2-Mercaptomet...) Show SMILES OC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C10H12O2S/c11-10(12)9(7-13)6-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against glutamate carboxypeptidase II (GCP II) using N-acetyl-L-aspartyl-[3H]-L-glutamate as a substrate				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II)				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50085699 ((S,S / R,R)4-Carboxy-5-[(2,4-dicarboxy-butyl)-hydr...) Show SMILES OC(=O)CCC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C12H19O10P/c13-9(14)3-1-7(11(17)18)5-23(21,22)6-8(12(19)20)2-4-10(15)16/h7-8H,1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106576 (2-[(2-Carboxy-propyl)-hydroxy-phosphinoylmethyl]-p...) Show SMILES CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H17O8P/c1-6(9(13)14)4-19(17,18)5-7(10(15)16)2-3-8(11)12/h6-7H,2-5H2,1H3,(H,11,12)(H,13,14)(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106577 (2-[(2-Carboxy-3-phenyl-propyl)-hydroxy-phosphinoyl...) Show SMILES OC(=O)CCC(CP(O)(=O)CC(Cc1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C16H21O8P/c17-14(18)7-6-12(15(19)20)9-25(23,24)10-13(16(21)22)8-11-4-2-1-3-5-11/h1-5,12-13H,6-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106570 (2-{Hydroxy-[(4-methoxy-phenylamino)-methyl]-phosph...) Show SMILES COc1ccc(NCP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H20NO7P/c1-22-12-5-3-11(4-6-12)15-9-23(20,21)8-10(14(18)19)2-7-13(16)17/h3-6,10,15H,2,7-9H2,1H3,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106566 (2-(Hydroxy-phenylaminomethyl-phosphinoylmethyl)-pe...) Show SMILES OC(=O)CCC(CP(O)(=O)CNc1ccccc1)C(O)=O Show InChI InChI=1S/C13H18NO6P/c15-12(16)7-6-10(13(17)18)8-21(19,20)9-14-11-4-2-1-3-5-11/h1-5,10,14H,6-9H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106575 (2-[Hydroxy-(hydroxy-pyridin-4-yl-methyl)-phosphino...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1ccncc1)C(O)=O Show InChI InChI=1S/C12H16NO7P/c14-10(15)2-1-9(11(16)17)7-21(19,20)12(18)8-3-5-13-6-4-8/h3-6,9,19-21H,1-2,7H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106567 (2-{[(3-Fluoro-phenyl)-hydroxy-methyl]-hydroxy-phos...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1cccc(F)c1)C(O)=O Show InChI InChI=1S/C13H16FO7P/c14-10-3-1-2-8(6-10)13(19)22(20,21)7-9(12(17)18)4-5-11(15)16/h1-3,6,9,20-22H,4-5,7H2,(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130578 (2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-5H-benzo[c][...) Show SMILES O=c1[nH]c2ccc(nc2c2ccccc12)N1C[C@H]2C[C@@H]1CN2 Show InChI InChI=1S/C17H16N4O/c22-17-13-4-2-1-3-12(13)16-14(19-17)5-6-15(20-16)21-9-10-7-11(21)8-18-10/h1-6,10-11,18H,7-9H2,(H,19,22)/t10-,11-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130575 (2-(4-Methyl-piperazin-1-yl)-5H-benzo[c][1,5]naphth...) Show SMILES CN1CCN(CC1)c1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C17H18N4O/c1-20-8-10-21(11-9-20)15-7-6-14-16(19-15)12-4-2-3-5-13(12)17(22)18-14/h2-7H,8-11H2,1H3,(H,18,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106564 (2-[(3,5-Difluoro-benzyl)-hydroxy-phosphinoylmethyl...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1cc(F)cc(F)c1)C(O)=O Show InChI InChI=1S/C13H15F2O6P/c14-10-3-8(4-11(15)5-10)6-22(20,21)7-9(13(18)19)1-2-12(16)17/h3-5,9H,1-2,6-7H2,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130576 (2-(5-Methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-5H-...) Show SMILES CN1C[C@H]2C[C@@H]1CN2c1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C18H18N4O/c1-21-9-12-8-11(21)10-22(12)16-7-6-15-17(20-16)13-4-2-3-5-14(13)18(23)19-15/h2-7,11-12H,8-10H2,1H3,(H,19,23)/t11-,12-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106568 (2-(Benzyl-hydroxy-phosphinoylmethyl)-pentanedioic ...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C13H17O6P/c14-12(15)7-6-11(13(16)17)9-20(18,19)8-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,14,15)(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106557 (2-[Hydroxy-(hydroxy-phenyl-methyl)-phosphinoylmeth...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1ccccc1)C(O)=O Show InChI InChI=1S/C13H17O7P/c14-11(15)7-6-10(12(16)17)8-21(19,20)13(18)9-4-2-1-3-5-9/h1-5,10,19-21H,6-8H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106560 (2-[(3,5-Bis-trifluoromethyl-benzyl)-hydroxy-phosph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(O)=O Show InChI InChI=1S/C15H15F6O6P/c16-14(17,18)10-3-8(4-11(5-10)15(19,20)21)6-28(26,27)7-9(13(24)25)1-2-12(22)23/h3-5,9H,1-2,6-7H2,(H,22,23)(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130568 (2-Piperazin-1-yl-5H-benzo[c][1,5]naphthyridin-6-on...) Show SMILES O=c1[nH]c2ccc(nc2c2ccccc12)N1CCNCC1 Show InChI InChI=1S/C16H16N4O/c21-16-12-4-2-1-3-11(12)15-13(18-16)5-6-14(19-15)20-9-7-17-8-10-20/h1-6,17H,7-10H2,(H,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106571 (2-[(Benzylamino-methyl)-hydroxy-phosphinoylmethyl]...) Show SMILES OC(=O)CCC(CP(O)(O)C=NCc1ccccc1)C(O)=O |w:11.11| Show InChI InChI=1S/C14H20NO6P/c16-13(17)7-6-12(14(18)19)9-22(20,21)10-15-8-11-4-2-1-3-5-11/h1-5,10,12,20-22H,6-9H2,(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106555 (2-[Hydroxy-(4-methyl-benzyl)-phosphinoylmethyl]-pe...) Show SMILES Cc1ccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H19O6P/c1-10-2-4-11(5-3-10)8-21(19,20)9-12(14(17)18)6-7-13(15)16/h2-5,12H,6-9H2,1H3,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130567 (2-(4-Cyclopropylmethyl-piperazin-1-yl)-5H-benzo[c]...) Show SMILES O=c1[nH]c2ccc(nc2c2ccccc12)N1CCN(CC2CC2)CC1 Show InChI InChI=1S/C20H22N4O/c25-20-16-4-2-1-3-15(16)19-17(21-20)7-8-18(22-19)24-11-9-23(10-12-24)13-14-5-6-14/h1-4,7-8,14H,5-6,9-13H2,(H,21,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130570 (2-(4-Pyrrolidin-1-yl-piperidin-1-yl)-5H-benzo[c][1...) Show SMILES O=c1[nH]c2ccc(nc2c2ccccc12)N1CCC(CC1)N1CCCC1 Show InChI InChI=1S/C21H24N4O/c26-21-17-6-2-1-5-16(17)20-18(22-21)7-8-19(23-20)25-13-9-15(10-14-25)24-11-3-4-12-24/h1-2,5-8,15H,3-4,9-14H2,(H,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM17752 (2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)methyl]ph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1c(F)c(F)c(F)c(F)c1F)C(O)=O Show InChI InChI=1S/C13H12F5O6P/c14-8-6(9(15)11(17)12(18)10(8)16)4-25(23,24)3-5(13(21)22)1-2-7(19)20/h5H,1-4H2,(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130582 (2-(4-Isopropyl-piperazin-1-yl)-N-(6-oxo-5,6-dihydr...) Show SMILES CC(C)N1CCN(CC(=O)Nc2cnc3c(c2)[nH]c(=O)c2ccccc32)CC1 Show InChI InChI=1S/C21H25N5O2/c1-14(2)26-9-7-25(8-10-26)13-19(27)23-15-11-18-20(22-12-15)16-5-3-4-6-17(16)21(28)24-18/h3-6,11-12,14H,7-10,13H2,1-2H3,(H,23,27)(H,24,28)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17755 (2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...) Show SMILES OC(=O)CCC(CCCS)C(O)=O Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II)				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106572 (2-[Hydroxy-(4-methoxy-benzyl)-phosphinoylmethyl]-p...) Show SMILES COc1ccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H19O7P/c1-21-12-5-2-10(3-6-12)8-22(19,20)9-11(14(17)18)4-7-13(15)16/h2-3,5-6,11H,4,7-9H2,1H3,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106558 (2-[(2-Benzyloxycarbonyl-propyl)-hydroxy-phosphinoy...) Show SMILES CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C17H23O8P/c1-12(17(22)25-9-13-5-3-2-4-6-13)10-26(23,24)11-14(16(20)21)7-8-15(18)19/h2-6,12,14H,7-11H2,1H3,(H,18,19)(H,20,21)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130577 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-benzo[c][1,5]...) Show SMILES CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C16H16N4O2/c1-20(2)9-14(21)18-13-8-7-12-15(19-13)10-5-3-4-6-11(10)16(22)17-12/h3-8H,9H2,1-2H3,(H,17,22)(H,18,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130593 (CHEMBL543159 | N-(6-Oxo-5,6-dihydro-benzo[c][1,5]n...) Show SMILES O=C(CN1CCCCC1)Nc1cnc2c(c1)[nH]c(=O)c1ccccc21 Show InChI InChI=1S/C19H20N4O2/c24-17(12-23-8-4-1-5-9-23)21-13-10-16-18(20-11-13)14-6-2-3-7-15(14)19(25)22-16/h2-3,6-7,10-11H,1,4-5,8-9,12H2,(H,21,24)(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130573 (2-(4-Dimethylamino-piperidin-1-yl)-5H-benzo[c][1,5...) Show SMILES CN(C)C1CCN(CC1)c1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C19H22N4O/c1-22(2)13-9-11-23(12-10-13)17-8-7-16-18(21-17)14-5-3-4-6-15(14)19(24)20-16/h3-8,13H,9-12H2,1-2H3,(H,20,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130585 (5H-Benzo[c][1,5]naphthyridin-6-one | CHEMBL320031 ...) Show SMILES O=c1[nH]c2cccnc2c2ccccc12 Show InChI InChI=1S/C12H8N2O/c15-12-9-5-2-1-4-8(9)11-10(14-12)6-3-7-13-11/h1-7H,(H,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130579 (5H-Benzo[c][1,6]naphthyridin-6-one | CHEMBL82342) Show SMILES O=c1[nH]c2ccncc2c2ccccc12 Show InChI InChI=1S/C12H8N2O/c15-12-9-4-2-1-3-8(9)10-7-13-6-5-11(10)14-12/h1-7H,(H,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130566 (CHEMBL542692 | N-(6-Oxo-5,6-dihydro-benzo[c][1,5]n...) Show SMILES O=C(CN1CCC(CC1)N1CCCC1)Nc1cnc2c(c1)[nH]c(=O)c1ccccc21 Show InChI InChI=1S/C23H27N5O2/c29-21(15-27-11-7-17(8-12-27)28-9-3-4-10-28)25-16-13-20-22(24-14-16)18-5-1-2-6-19(18)23(30)26-20/h1-2,5-6,13-14,17H,3-4,7-12,15H2,(H,25,29)(H,26,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130572 (CHEMBL545507 | N-(6-Oxo-5,6-dihydro-benzo[c][1,5]n...) Show SMILES O=C(CN1CCC(CC1)N1CCCC1)Nc1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C23H27N5O2/c29-21(15-27-13-9-16(10-14-27)28-11-3-4-12-28)25-20-8-7-19-22(26-20)17-5-1-2-6-18(17)23(30)24-19/h1-2,5-8,16H,3-4,9-15H2,(H,24,30)(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106563 (2-[(3-Amino-benzyl)-hydroxy-phosphinoylmethyl]-pen...) Show SMILES Nc1cccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)c1 Show InChI InChI=1S/C13H18NO6P/c14-11-3-1-2-9(6-11)7-21(19,20)8-10(13(17)18)4-5-12(15)16/h1-3,6,10H,4-5,7-8,14H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106578 (2-(Hydroxy-phenethyl-phosphinoylmethyl)-pentanedio...) Show SMILES OC(=O)CCC(CP(O)(=O)CCc1ccccc1)C(O)=O Show InChI InChI=1S/C14H19O6P/c15-13(16)7-6-12(14(17)18)10-21(19,20)9-8-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130569 (CHEMBL542927 | N-(6-Oxo-5,6-dihydro-benzo[c][1,5]n...) Show SMILES O=C(CN1CCCCC1)Nc1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C19H20N4O2/c24-17(12-23-10-4-1-5-11-23)21-16-9-8-15-18(22-16)13-6-2-3-7-14(13)19(25)20-15/h2-3,6-9H,1,4-5,10-12H2,(H,20,25)(H,21,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106565 (2-[(2-Fluoro-benzyl)-hydroxy-phosphinoylmethyl]-pe...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1ccccc1F)C(O)=O Show InChI InChI=1S/C13H16FO6P/c14-11-4-2-1-3-9(11)7-21(19,20)8-10(13(17)18)5-6-12(15)16/h1-4,10H,5-8H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130586 (2-Dimethylamino-N-(6-oxo-5,6-dihydro-benzo[c][1,5]...) Show SMILES CN(C)CC(=O)Nc1cnc2c(c1)[nH]c(=O)c1ccccc21 Show InChI InChI=1S/C16H16N4O2/c1-20(2)9-14(21)18-10-7-13-15(17-8-10)11-5-3-4-6-12(11)16(22)19-13/h3-8H,9H2,1-2H3,(H,18,21)(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130590 (5H-Benzo[c][1,7]naphthyridin-6-one | CHEMBL311091) Show SMILES O=c1[nH]c2cnccc2c2ccccc12 Show InChI InChI=1S/C12H8N2O/c15-12-10-4-2-1-3-8(10)9-5-6-13-7-11(9)14-12/h1-7H,(H,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130589 (2-(2-Diethylamino-ethylamino)-5H-benzo[c][1,5]naph...) Show SMILES CCN(CC)CCNc1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C18H22N4O/c1-3-22(4-2)12-11-19-16-10-9-15-17(21-16)13-7-5-6-8-14(13)18(23)20-15/h5-10H,3-4,11-12H2,1-2H3,(H,19,21)(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106554 (2-Phosphonomethyl-4-(5H-tetrazol-5-yl)-butyric aci...) Show SMILES OC(=O)C(CCc1nnn[nH]1)CP(O)(O)=O Show InChI InChI=1S/C6H11N4O5P/c11-6(12)4(3-16(13,14)15)1-2-5-7-9-10-8-5/h4H,1-3H2,(H,11,12)(H2,13,14,15)(H,7,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130580 (3-Amino-5H-benzo[c][1,5]naphthyridin-6-one | 3-ami...) Show SMILES Nc1cnc2c(c1)[nH]c(=O)c1ccccc21 Show InChI InChI=1S/C12H9N3O/c13-7-5-10-11(14-6-7)8-3-1-2-4-9(8)12(16)15-10/h1-6H,13H2,(H,15,16)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106556 (2-Phosphonomethyl-hexanedioic acid | CHEMBL334737) Show SMILES OC(=O)CCCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C7H13O7P/c8-6(9)3-1-2-5(7(10)11)4-15(12,13)14/h5H,1-4H2,(H,8,9)(H,10,11)(H2,12,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23174 (6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...) Show SMILES Clc1ccc2c(c1)o[nH]c2=O Show InChI InChI=1S/C7H4ClNO2/c8-4-1-2-5-6(3-4)11-9-7(5)10/h1-3H,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106562 (4-Phenyl-2-phosphonomethyl-butyric acid | CHEMBL13...) Show SMILES OC(=O)C(CCc1ccccc1)CP(O)(O)=O Show InChI InChI=1S/C11H15O5P/c12-11(13)10(8-17(14,15)16)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,12,13)(H2,14,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50110796 ((4-(6-amino-9H-purin-9-yl)cyclopent-2-enyloxy)meth...) Show SMILES Nc1ncnc2n(cnc12)C1CC(OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=C1 |c:29| Show InChI InChI=1S/C11H16N5O10P3/c12-10-9-11(14-4-13-10)16(5-15-9)7-1-2-8(3-7)24-6-27(17,18)25-29(22,23)26-28(19,20)21/h1-2,4-5,7-8H,3,6H2,(H,17,18)(H,22,23)(H2,12,13,14)(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DNA synthesis by HIV reverse transcriptase				J Med Chem 45: 1284-91 (2002) BindingDB Entry DOI: 10.7270/Q2PR7V9F
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130571 (2-Amino-5H-benzo[c][1,5]naphthyridin-6-one | CHEMB...) Show SMILES Nc1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C12H9N3O/c13-10-6-5-9-11(15-10)7-3-1-2-4-8(7)12(16)14-9/h1-6H,(H2,13,15)(H,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130574 (2-(4-Methyl-4-oxy-piperazin-1-yl)-5H-benzo[c][1,5]...) Show SMILES C[N+]1([O-])CCN(CC1)c1ccc2[nH]c(=O)c3ccccc3c2n1 Show InChI InChI=1S/C17H18N4O2/c1-21(23)10-8-20(9-11-21)15-7-6-14-16(19-15)12-4-2-3-5-13(12)17(22)18-14/h2-7H,8-11H2,1H3,(H,18,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair

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