Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'stoermer' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against glutamate carboxypeptidase II (GCP II) using N-acetyl-L-aspartyl-[3H]-L-glutamate as a substrate				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration of the compound required for the neuroprotective effect determined by inhibition of GCP II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM50129200 ((R)-2-Amino-4-methyl-pentanoic acid hydroxyamide |...) Show SMILES CC(C)C[C@@H](N)C(=O)NO Show InChI InChI=1S/C6H14N2O2/c1-4(2)3-5(7)6(9)8-10/h4-5,10H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of metalloprotease from family M28, Aeromonas proteolytica aminopeptidase				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50109593 (2-Benzyl-3-mercapto-propionic acid | 2-Mercaptomet...) Show SMILES OC(=O)C(CS)Cc1ccccc1 Show InChI InChI=1S/C10H12O2S/c11-10(12)9(7-13)6-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against glutamate carboxypeptidase II (GCP II) using N-acetyl-L-aspartyl-[3H]-L-glutamate as a substrate				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair
Bacterial leucyl aminopeptidase (Vibrio proteolyticus)	BDBM50129202 ((S)-2-Amino-4-methyl-pentanoic acid hydroxyamide |...) Show SMILES CC(C)C[C@H](N)C(=O)NO Show InChI InChI=1S/C6H14N2O2/c1-4(2)3-5(7)6(9)8-10/h4-5,10H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of metalloprotease from family M28, Aeromonas proteolytica aminopeptidase				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Glutamate carboxypeptidase II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II)				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17659 ((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...) Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50085699 ((S,S / R,R)4-Carboxy-5-[(2,4-dicarboxy-butyl)-hydr...) Show SMILES OC(=O)CCC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C12H19O10P/c13-9(14)3-1-7(11(17)18)5-23(21,22)6-8(12(19)20)2-4-10(15)16/h7-8H,1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106576 (2-[(2-Carboxy-propyl)-hydroxy-phosphinoylmethyl]-p...) Show SMILES CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H17O8P/c1-6(9(13)14)4-19(17,18)5-7(10(15)16)2-3-8(11)12/h6-7H,2-5H2,1H3,(H,11,12)(H,13,14)(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392045 (CHEMBL2152561) Show SMILES OC(=O)c1cccc(c1)-c1cccc(CCS)c1C(O)=O Show InChI InChI=1S/C16H14O4S/c17-15(18)12-5-1-4-11(9-12)13-6-2-3-10(7-8-21)14(13)16(19)20/h1-6,9,21H,7-8H2,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392040 (CHEMBL2152556) Show SMILES OC(=O)c1cccc(COc2ccc(CS)cc2C(O)=O)c1 Show InChI InChI=1S/C16H14O5S/c17-15(18)12-3-1-2-10(6-12)8-21-14-5-4-11(9-22)7-13(14)16(19)20/h1-7,22H,8-9H2,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106577 (2-[(2-Carboxy-3-phenyl-propyl)-hydroxy-phosphinoyl...) Show SMILES OC(=O)CCC(CP(O)(=O)CC(Cc1ccccc1)C(O)=O)C(O)=O Show InChI InChI=1S/C16H21O8P/c17-14(18)7-6-12(15(19)20)9-25(23,24)10-13(16(21)22)8-11-4-2-1-3-5-11/h1-5,12-13H,6-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106570 (2-{Hydroxy-[(4-methoxy-phenylamino)-methyl]-phosph...) Show SMILES COc1ccc(NCP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H20NO7P/c1-22-12-5-3-11(4-6-12)15-9-23(20,21)8-10(14(18)19)2-7-13(16)17/h3-6,10,15H,2,7-9H2,1H3,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106566 (2-(Hydroxy-phenylaminomethyl-phosphinoylmethyl)-pe...) Show SMILES OC(=O)CCC(CP(O)(=O)CNc1ccccc1)C(O)=O Show InChI InChI=1S/C13H18NO6P/c15-12(16)7-6-10(13(17)18)8-21(19,20)9-14-11-4-2-1-3-5-11/h1-5,10,14H,6-9H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392046 (CHEMBL2152562) Show SMILES OC(=O)c1ccc(cc1)-c1cccc(CCS)c1C(O)=O Show InChI InChI=1S/C16H14O4S/c17-15(18)12-6-4-10(5-7-12)13-3-1-2-11(8-9-21)14(13)16(19)20/h1-7,21H,8-9H2,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106575 (2-[Hydroxy-(hydroxy-pyridin-4-yl-methyl)-phosphino...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1ccncc1)C(O)=O Show InChI InChI=1S/C12H16NO7P/c14-10(15)2-1-9(11(16)17)7-21(19,20)12(18)8-3-5-13-6-4-8/h3-6,9,19-21H,1-2,7H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17775 (3-(1-carboxy-4-sulfanylbutoxy)benzoic acid | Thiol...) Show SMILES OC(=O)C(CCCS)Oc1cccc(c1)C(O)=O Show InChI InChI=1S/C12H14O5S/c13-11(14)8-3-1-4-9(7-8)17-10(12(15)16)5-2-6-18/h1,3-4,7,10,18H,2,5-6H2,(H,13,14)(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17762 (3-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...) Show SMILES OC(=O)C(CCCS)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C13H16O4S/c14-12(15)10-4-1-3-9(7-10)8-11(13(16)17)5-2-6-18/h1,3-4,7,11,18H,2,5-6,8H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17762 (3-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...) Show SMILES OC(=O)C(CCCS)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C13H16O4S/c14-12(15)10-4-1-3-9(7-10)8-11(13(16)17)5-2-6-18/h1,3-4,7,11,18H,2,5-6,8H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392041 (CHEMBL2152557) Show SMILES OC(=O)c1ccc(COc2ccc(CS)cc2C(O)=O)cc1 Show InChI InChI=1S/C16H14O5S/c17-15(18)12-4-1-10(2-5-12)8-21-14-6-3-11(9-22)7-13(14)16(19)20/h1-7,22H,8-9H2,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106567 (2-{[(3-Fluoro-phenyl)-hydroxy-methyl]-hydroxy-phos...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1cccc(F)c1)C(O)=O Show InChI InChI=1S/C13H16FO7P/c14-10-3-1-2-8(6-10)13(19)22(20,21)7-9(12(17)18)4-5-11(15)16/h1-3,6,9,20-22H,4-5,7H2,(H,15,16)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50332228 (1-(3-Carboxyphenyl)-3-(2-mercapto-ethyl)-1H-indole...) Show SMILES OC(=O)c1c(CCS)c2ccccc2n1-c1cccc(c1)C(O)=O Show InChI InChI=1S/C18H15NO4S/c20-17(21)11-4-3-5-12(10-11)19-15-7-2-1-6-13(15)14(8-9-24)16(19)18(22)23/h1-7,10,24H,8-9H2,(H,20,21)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17776 (3-[(1-carboxy-4-sulfanylbutyl)sulfanyl]benzoic aci...) Show SMILES OC(=O)C(CCCS)Sc1cccc(c1)C(O)=O Show InChI InChI=1S/C12H14O4S2/c13-11(14)8-3-1-4-9(7-8)18-10(12(15)16)5-2-6-17/h1,3-4,7,10,17H,2,5-6H2,(H,13,14)(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392036 (CHEMBL2152437) Show SMILES OC(=O)c1cccc(c1)-c1ccc(CS)cc1C(O)=O Show InChI InChI=1S/C15H12O4S/c16-14(17)11-3-1-2-10(7-11)12-5-4-9(8-20)6-13(12)15(18)19/h1-7,20H,8H2,(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392039 (CHEMBL2152555) Show SMILES OC(=O)c1ccccc1COc1ccc(CS)cc1C(O)=O Show InChI InChI=1S/C16H14O5S/c17-15(18)12-4-2-1-3-11(12)8-21-14-6-5-10(9-22)7-13(14)16(19)20/h1-7,22H,8-9H2,(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106564 (2-[(3,5-Difluoro-benzyl)-hydroxy-phosphinoylmethyl...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1cc(F)cc(F)c1)C(O)=O Show InChI InChI=1S/C13H15F2O6P/c14-10-3-8(4-11(15)5-10)6-22(20,21)7-9(13(18)19)1-2-12(16)17/h3-5,9H,1-2,6-7H2,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392037 (CHEMBL2152438) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(CS)cc1C(O)=O Show InChI InChI=1S/C15H12O4S/c16-14(17)11-4-2-10(3-5-11)12-6-1-9(8-20)7-13(12)15(18)19/h1-7,20H,8H2,(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106568 (2-(Benzyl-hydroxy-phosphinoylmethyl)-pentanedioic ...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C13H17O6P/c14-12(15)7-6-11(13(16)17)9-20(18,19)8-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,14,15)(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106557 (2-[Hydroxy-(hydroxy-phenyl-methyl)-phosphinoylmeth...) Show SMILES OC(=O)CCC(CP(O)(O)C(=O)c1ccccc1)C(O)=O Show InChI InChI=1S/C13H17O7P/c14-11(15)7-6-10(12(16)17)8-21(19,20)13(18)9-4-2-1-3-5-9/h1-5,10,19-21H,6-8H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106560 (2-[(3,5-Bis-trifluoromethyl-benzyl)-hydroxy-phosph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(O)=O Show InChI InChI=1S/C15H15F6O6P/c16-14(17,18)10-3-8(4-11(5-10)15(19,20)21)6-28(26,27)7-9(13(24)25)1-2-12(22)23/h3-5,9H,1-2,6-7H2,(H,22,23)(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106571 (2-[(Benzylamino-methyl)-hydroxy-phosphinoylmethyl]...) Show SMILES OC(=O)CCC(CP(O)(O)C=NCc1ccccc1)C(O)=O |w:11.11| Show InChI InChI=1S/C14H20NO6P/c16-13(17)7-6-12(14(18)19)9-22(20,21)10-15-8-11-4-2-1-3-5-11/h1-5,10,12,20-22H,6-9H2,(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17763 (4-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...) Show SMILES OC(=O)C(CCCS)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C13H16O4S/c14-12(15)10-5-3-9(4-6-10)8-11(13(16)17)2-1-7-18/h3-6,11,18H,1-2,7-8H2,(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106555 (2-[Hydroxy-(4-methyl-benzyl)-phosphinoylmethyl]-pe...) Show SMILES Cc1ccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H19O6P/c1-10-2-4-11(5-3-10)8-21(19,20)9-12(14(17)18)6-7-13(15)16/h2-5,12H,6-9H2,1H3,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392049 (CHEMBL2152565) Show SMILES OC(=O)c1cccc(COc2cccc(CCS)c2C(O)=O)c1 Show InChI InChI=1S/C17H16O5S/c18-16(19)13-5-1-3-11(9-13)10-22-14-6-2-4-12(7-8-23)15(14)17(20)21/h1-6,9,23H,7-8,10H2,(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17752 (2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)methyl]ph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1c(F)c(F)c(F)c(F)c1F)C(O)=O Show InChI InChI=1S/C13H12F5O6P/c14-8-6(9(15)11(17)12(18)10(8)16)4-25(23,24)3-5(13(21)22)1-2-7(19)20/h5H,1-4H2,(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Glutamate carboxypeptidase II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17752 (2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)methyl]ph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1c(F)c(F)c(F)c(F)c1F)C(O)=O Show InChI InChI=1S/C13H12F5O6P/c14-8-6(9(15)11(17)12(18)10(8)16)4-25(23,24)3-5(13(21)22)1-2-7(19)20/h5H,1-4H2,(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM17752 (2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)methyl]ph...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1c(F)c(F)c(F)c(F)c1F)C(O)=O Show InChI InChI=1S/C13H12F5O6P/c14-8-6(9(15)11(17)12(18)10(8)16)4-25(23,24)3-5(13(21)22)1-2-7(19)20/h5H,1-4H2,(H,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17755 (2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...) Show SMILES OC(=O)CCC(CCCS)C(O)=O Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II)				J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17755 (2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...) Show SMILES OC(=O)CCC(CCCS)C(O)=O Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106572 (2-[Hydroxy-(4-methoxy-benzyl)-phosphinoylmethyl]-p...) Show SMILES COc1ccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)cc1 Show InChI InChI=1S/C14H19O7P/c1-21-12-5-2-10(3-6-12)8-22(19,20)9-11(14(17)18)4-7-13(15)16/h2-3,5-6,11H,4,7-9H2,1H3,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM17755 (2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...) Show SMILES OC(=O)CCC(CCCS)C(O)=O Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Glutamate carboxypeptidase II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17755 (2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...) Show SMILES OC(=O)CCC(CCCS)C(O)=O Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106558 (2-[(2-Benzyloxycarbonyl-propyl)-hydroxy-phosphinoy...) Show SMILES CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C17H23O8P/c1-12(17(22)25-9-13-5-3-2-4-6-13)10-26(23,24)11-14(16(20)21)7-8-15(18)19/h2-6,12,14H,7-11H2,1H3,(H,18,19)(H,20,21)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 [44-750] (Homo sapiens (Human))	BDBM17777 (3-[2-carboxy-2-(phosphonomethyl)ethyl]benzoic acid...) Show SMILES OC(=O)C(Cc1cccc(c1)C(O)=O)CP(O)(O)=O Show InChI InChI=1S/C11H13O7P/c12-10(13)8-3-1-2-7(4-8)5-9(11(14)15)6-19(16,17)18/h1-4,9H,5-6H2,(H,12,13)(H,14,15)(H2,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM50392048 (CHEMBL2152564) Show SMILES OC(=O)c1ccccc1COc1cccc(CCS)c1C(O)=O Show InChI InChI=1S/C17H16O5S/c18-16(19)13-6-2-1-4-12(13)10-22-14-7-3-5-11(8-9-23)15(14)17(20)21/h1-7,23H,8-10H2,(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay				J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106563 (2-[(3-Amino-benzyl)-hydroxy-phosphinoylmethyl]-pen...) Show SMILES Nc1cccc(CP(O)(=O)CC(CCC(O)=O)C(O)=O)c1 Show InChI InChI=1S/C13H18NO6P/c14-11-3-1-2-9(6-11)7-21(19,20)8-10(13(17)18)4-5-12(15)16/h1-3,6,10H,4-5,7-8,14H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106578 (2-(Hydroxy-phenethyl-phosphinoylmethyl)-pentanedio...) Show SMILES OC(=O)CCC(CP(O)(=O)CCc1ccccc1)C(O)=O Show InChI InChI=1S/C14H19O6P/c15-13(16)7-6-12(14(17)18)10-21(19,20)9-8-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Rattus norvegicus)	BDBM50106565 (2-[(2-Fluoro-benzyl)-hydroxy-phosphinoylmethyl]-pe...) Show SMILES OC(=O)CCC(CP(O)(=O)Cc1ccccc1F)C(O)=O Show InChI InChI=1S/C13H16FO6P/c14-11-4-2-1-3-9(11)7-21(19,20)8-10(13(17)18)5-6-12(15)16/h1-4,10H,5-8H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase)				J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8
					More data for this Ligand-Target Pair

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