| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50564178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2086972 (CHEMBL4768235) |
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| Ki | 4.1±n/a nM |
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| Citation |  Xiong, J; Jin, J; Gao, L; Hao, C; Liu, X; Liu, BF; Chen, Y; Zhang, G Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain. Eur J Med Chem191:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50564178 |
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| n/a |
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| Name | BDBM50564178 |
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| Synonyms: | CHEMBL4785048 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29FN2O |
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| Mol. Mass. | 368.4876 |
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| SMILES | CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1 |
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| Structure | 
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