| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin-3 receptor 1 |
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| Ligand | BDBM50581009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2149556 (CHEMBL5033954) |
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| Ki | 268±n/a nM |
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| Citation |  Guan, D; Rahman, MT; Gay, EA; Vasukuttan, V; Mathews, KM; Decker, AM; Williams, AH; Zhan, CG; Jin, C Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies. J Med Chem64:17866-17886 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin-3 receptor 1 |
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| Name: | Relaxin-3 receptor 1 |
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| Synonyms: | G protein-coupled receptor SALPR | G-protein coupled receptor GPCR135 | GPCR135 | RL3R1_HUMAN | RLN3 receptor 1 | RLN3R1 | RXFP3 | Relaxin family peptide receptor 3 | SALPR | Somatostatin- and angiotensin-like peptide receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51139.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_818423 |
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| Residue: | 469 |
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| Sequence: | MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA
PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF
VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR
YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK
VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA
GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS
QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA
TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
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| BDBM50581009 |
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| n/a |
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| Name | BDBM50581009 |
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| Synonyms: | CHEMBL5094670 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N6O |
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| Mol. Mass. | 374.439 |
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| SMILES | COc1cc(C)c2[nH]cc(\C=N\NC(=N)NCCc3ccc(cc3)C#N)c2c1 |
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| Structure | 
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