| Reaction Details |
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 | Report a problem with these data |
| Target | Relaxin-3 receptor 2 |
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| Ligand | BDBM50581019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2149557 (CHEMBL5033955) |
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| EC50 | 2.7±n/a nM |
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| Citation |  Guan, D; Rahman, MT; Gay, EA; Vasukuttan, V; Mathews, KM; Decker, AM; Williams, AH; Zhan, CG; Jin, C Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies. J Med Chem64:17866-17886 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Relaxin-3 receptor 2 |
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| Name: | Relaxin-3 receptor 2 |
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| Synonyms: | G-protein coupled receptor 100 | G-protein coupled receptor GPCR142 | GPCR142 | GPR100 | Insulin-like peptide INSL5 receptor | RL3R2_HUMAN | RLN3 receptor 2 | RLN3R2 | RXFP4 | Relaxin family peptide receptor 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41161.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456194 |
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| Residue: | 374 |
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| Sequence: | MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR
PSTLLTNLDRGTPG
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| BDBM50581019 |
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| n/a |
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| Name | BDBM50581019 |
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| Synonyms: | CHEMBL5089949 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N6O2 |
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| Mol. Mass. | 402.4491 |
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| SMILES | COC(=O)c1ccc(CCNC(=N)N\N=C\c2c[nH]c3c(C)cc(cc23)C#N)cc1 |
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| Structure | 
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