| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor 1 |
|---|
| Ligand | BDBM50004927 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_90137 |
|---|
| Ki | >100000±n/a nM |
|---|
| Citation |  Whitten, JP; Baron, BM; Muench, D; Miller, F; White, HS; McDonald, IA (R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex. J Med Chem33:2961-3 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor 1 |
|---|
| Name: | Glutamate receptor 1 |
|---|
| Synonyms: | AMPA-selective glutamate receptor 1 | GRIA1_RAT | GluA1 | GluR-1 | GluR-A | GluR-K1 | Glur1 | Glutamate receptor ionotropic, AMPA 1 | Gria1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 101583.91 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P19490 |
|---|
| Residue: | 907 |
|---|
| Sequence: | MPYIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID
IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ
FVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTT
TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL
NKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVM
AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR
RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV
MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE
LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW
MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ
QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA
YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES
TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW
WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK
GFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIPCMSHSSGM
PLGATGL
|
|
|
|---|
| BDBM50004927 |
|---|
| n/a |
|---|
| Name | BDBM50004927 |
|---|
| Synonyms: | 4-Phosphonomethyl-piperidine-2-carboxylic acid | 4-Phosphonomethyl-piperidine-2-carboxylic acid (CGS-19755, LY 272541) | CGS 19755 | CGS-19755 | CHEMBL39664 | Selfotel | cis-(+)-((2S,4R)-4-Phosphonomethyl-piperidine-2-carboxylic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H14NO5P |
|---|
| Mol. Mass. | 223.1635 |
|---|
| SMILES | OC(=O)[C@@H]1C[C@H](CP(O)(O)=O)CCN1 |
|---|
| Structure | 
|
|---|
Search and Browse
