Compile Data Set for Download or QSAR

Found 932 hits with Last Name = 'whitten' and Initial = 'jp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054245 (5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1Cl Show InChI InChI=1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054252 (5-Bromo-N-cyclopropylmethyl-2-methyl-N-propyl-N'-(...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1Br Show InChI InChI=1S/C18H20BrCl3N4/c1-3-6-26(9-11-4-5-11)18-15(19)17(23-10(2)24-18)25-16-13(21)7-12(20)8-14(16)22/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054250 (CHEMBL306482 | N-Cyclopropylmethyl-2,5-dimethyl-N-...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C19H23Cl3N4/c1-4-7-26(10-13-5-6-13)19-11(2)18(23-12(3)24-19)25-17-15(21)8-14(20)9-16(17)22/h8-9,13H,4-7,10H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054248 (2,5-Dimethyl-N,N-dipropyl-N'-(2,4,6-trichloro-phen...) Show SMILES CCCN(CCC)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C18H23Cl3N4/c1-5-7-25(8-6-2)18-11(3)17(22-12(4)23-18)24-16-14(20)9-13(19)10-15(16)21/h9-10H,5-8H2,1-4H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054253 (CHEMBL77716 | N-Cyclopropylmethyl-5-ethyl-2-methyl...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1CC Show InChI InChI=1S/C20H25Cl3N4/c1-4-8-27(11-13-6-7-13)20-15(5-2)19(24-12(3)25-20)26-18-16(22)9-14(21)10-17(18)23/h9-10,13H,4-8,11H2,1-3H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384714 (CHEMBL2037200) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144204 (CHEMBL63989 | [4-(2-Chloro-4,6-dimethoxy-phenyl)-p...) Show SMILES CCCN(C(C1CC1)C1CC1)c1nccc(n1)-c1c(Cl)cc(OC)cc1OC Show InChI InChI=1S/C22H28ClN3O2/c1-4-11-26(21(14-5-6-14)15-7-8-15)22-24-10-9-18(25-22)20-17(23)12-16(27-2)13-19(20)28-3/h9-10,12-15,21H,4-8,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144193 (CHEMBL65484 | Dicyclopropylmethyl-propyl-[4-(2,4,6...) Show SMILES CCCN(C(C1CC1)C1CC1)c1nccc(n1)-c1c(OC)cc(OC)cc1OC Show InChI InChI=1S/C23H31N3O3/c1-5-12-26(22(15-6-7-15)16-8-9-16)23-24-11-10-18(25-23)21-19(28-3)13-17(27-2)14-20(21)29-4/h10-11,13-16,22H,5-9,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144191 (CHEMBL61954 | Dicyclopropylmethyl-[4-(2,4-dimethox...) Show SMILES CCCN(C(C1CC1)C1CC1)c1ncc(C)c(n1)-c1c(C)cc(OC)cc1OC |(15.35,-8.38,;15.35,-6.84,;14.01,-6.08,;13.99,-4.54,;15.32,-3.75,;15.32,-2.21,;16.09,-.87,;14.55,-.89,;16.67,-4.52,;17.44,-5.85,;18.2,-4.52,;12.66,-3.77,;12.65,-2.22,;11.3,-1.46,;9.97,-2.23,;8.64,-1.47,;9.98,-3.77,;11.32,-4.54,;8.66,-4.54,;8.66,-6.1,;9.99,-6.87,;7.32,-6.87,;5.99,-6.1,;4.65,-6.86,;4.65,-8.4,;5.99,-4.56,;7.32,-3.77,;7.32,-2.25,;5.97,-1.48,)| Show InChI InChI=1S/C24H33N3O2/c1-6-11-27(23(17-7-8-17)18-9-10-18)24-25-14-16(3)22(26-24)21-15(2)12-19(28-4)13-20(21)29-5/h12-14,17-18,23H,6-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144194 (CHEMBL293627 | Dicyclopropylmethyl-[4-(2,4-dimetho...) Show SMILES CCCN(C(C1CC1)C1CC1)c1ncc(C)c(n1)-c1ccc(OC)cc1OC Show InChI InChI=1S/C23H31N3O2/c1-5-12-26(22(16-6-7-16)17-8-9-17)23-24-14-15(2)21(25-23)19-11-10-18(27-3)13-20(19)28-4/h10-11,13-14,16-17,22H,5-9,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054246 (CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(Cl)cc(Cl)cc2Cl)nc(C)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)17-9-16(22-11(2)23-17)24-18-14(20)7-13(19)8-15(18)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144196 (CHEMBL63029 | [4-(4-Bromo-phenyl)-5-methyl-pyrimid...) Show SMILES CCCN(C(C1CC1)C1CC1)c1ncc(C)c(n1)-c1ccc(Br)cc1 Show InChI InChI=1S/C21H26BrN3/c1-3-12-25(20(16-4-5-16)17-6-7-17)21-23-13-14(2)19(24-21)15-8-10-18(22)11-9-15/h8-11,13,16-17,20H,3-7,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054225 (CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C20H29N5/c1-6-9-25(12-17-7-8-17)20-22-16(5)21-19(24-20)23-18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144197 (CHEMBL66249 | [4-(4-Bromo-2-methyl-phenyl)-5-methy...) Show SMILES CCCN(C(C1CC1)C1CC1)c1ncc(C)c(n1)-c1ccc(Br)cc1C Show InChI InChI=1S/C22H28BrN3/c1-4-11-26(21(16-5-6-16)17-7-8-17)22-24-13-15(3)20(25-22)19-10-9-18(23)12-14(19)2/h9-10,12-13,16-17,21H,4-8,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144200 (CHEMBL63457 | Dicyclopropylmethyl-[4-(2-fluoro-4,6...) Show SMILES CCCN(C(C1CC1)C1CC1)c1nccc(n1)-c1c(F)cc(OC)cc1OC Show InChI InChI=1S/C22H28FN3O2/c1-4-11-26(21(14-5-6-14)15-7-8-15)22-24-10-9-18(25-22)20-17(23)12-16(27-2)13-19(20)28-3/h9-10,12-15,21H,4-8,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054249 (CHEMBL140175 | N*4*-Cyclopropylmethyl-6-methyl-N*4...) Show SMILES CCCN(CC1CC1)c1cc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)16-7-11(2)22-18(23-16)24-17-14(20)8-13(19)9-15(17)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144203 (Allyl-dicyclopropylmethyl-[4-(2,4,6-trimethoxy-phe...) Show SMILES COc1cc(OC)c(c(OC)c1)-c1ccnc(n1)N(CC=C)C(C1CC1)C1CC1 Show InChI InChI=1S/C23H29N3O3/c1-5-12-26(22(15-6-7-15)16-8-9-16)23-24-11-10-18(25-23)21-19(28-3)13-17(27-2)14-20(21)29-4/h5,10-11,13-16,22H,1,6-9,12H2,2-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054226 (CHEMBL77391 | N,N-Diallyl-6-methyl-N'-(2,4,6-trime...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N(CC=C)CC=C)c(C)c1 Show InChI InChI=1S/C19H25N5/c1-7-9-24(10-8-2)19-21-16(6)20-18(23-19)22-17-14(4)11-13(3)12-15(17)5/h7-8,11-12H,1-2,9-10H2,3-6H3,(H,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054230 (6-Methyl-N,N-dipropyl-N'-(2,4,6-trimethyl-phenyl)-...) Show SMILES CCCN(CCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C19H29N5/c1-7-9-24(10-8-2)19-21-16(6)20-18(23-19)22-17-14(4)11-13(3)12-15(17)5/h11-12H,7-10H2,1-6H3,(H,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054247 (CHEMBL344805 | N-Cyclopropylmethyl-2,5,N'-trimethy...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(N(C)c2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C20H25Cl3N4/c1-5-8-27(11-14-6-7-14)20-12(2)19(24-13(3)25-20)26(4)18-16(22)9-15(21)10-17(18)23/h9-10,14H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144202 (((R)-Cyclopropyl-phenyl-methyl)-propyl-[4-(2,4,6-t...) Show SMILES CCCN([C@H](C1CC1)c1ccccc1)c1nccc(n1)-c1c(OC)cc(OC)cc1OC Show InChI InChI=1S/C26H31N3O3/c1-5-15-29(25(19-11-12-19)18-9-7-6-8-10-18)26-27-14-13-21(28-26)24-22(31-3)16-20(30-2)17-23(24)32-4/h6-10,13-14,16-17,19,25H,5,11-12,15H2,1-4H3/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144192 (CHEMBL291657 | [4-(4-Bromo-phenyl)-5,6-dimethyl-py...) Show SMILES COc1cc(Cl)c(cc1C)-c1nc(sc1C)N(CC#C)[C@@H](CC1CC1)c1ccc(C)c(F)c1 Show InChI InChI=1S/C27H28ClFN2OS/c1-6-11-31(24(13-19-8-9-19)20-10-7-16(2)23(29)14-20)27-30-26(18(4)33-27)21-12-17(3)25(32-5)15-22(21)28/h1,7,10,12,14-15,19,24H,8-9,11,13H2,2-5H3/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144190 (CHEMBL302396 | Propyl-(1-thiophen-2-yl-cyclopropyl...) Show SMILES CCCN(c1nccc(n1)-c1c(OC)cc(OC)cc1OC)C1(CC1)c1cccs1 Show InChI InChI=1S/C23H27N3O3S/c1-5-12-26(23(9-10-23)20-7-6-13-30-20)22-24-11-8-17(25-22)21-18(28-3)14-16(27-2)15-19(21)29-4/h6-8,11,13-15H,5,9-10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054244 (CHEMBL134475 | N-Cyclopropylmethyl-2-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1cc(Nc2cc(Cl)c(Cl)cc2Cl)nc(C)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)18-9-17(22-11(2)23-18)24-16-8-14(20)13(19)7-15(16)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	253	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144201 (CHEMBL305354 | Dicyclopropylmethyl-[4-(2,4-dimetho...) Show SMILES CCCN(C(C1CC1)C1CC1)c1nccc(n1)-c1ccc(OC)cc1OC Show InChI InChI=1S/C22H29N3O2/c1-4-13-25(21(15-5-6-15)16-7-8-16)22-23-12-11-19(24-22)18-10-9-17(26-2)14-20(18)27-3/h9-12,14-16,21H,4-8,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054221 (CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...) Show SMILES CCCCN(CCCC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C21H33N5/c1-7-9-11-26(12-10-8-2)21-23-18(6)22-20(25-21)24-19-16(4)13-15(3)14-17(19)5/h13-14H,7-12H2,1-6H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054216 (CHEMBL307419 | N-Benzyl-6-methyl-N-propyl-N'-(2,4,...) Show SMILES CCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C23H29N5/c1-6-12-28(15-20-10-8-7-9-11-20)23-25-19(5)24-22(27-23)26-21-17(3)13-16(2)14-18(21)4/h7-11,13-14H,6,12,15H2,1-5H3,(H,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144199 ((1-Furan-3-yl-cyclopropyl)-propyl-[4-(2,4,6-trimet...) Show SMILES CCCN(c1nccc(n1)-c1c(OC)cc(OC)cc1OC)C1(CC1)c1ccoc1 Show InChI InChI=1S/C23H27N3O4/c1-5-11-26(23(8-9-23)16-7-12-30-15-16)22-24-10-6-18(25-22)21-19(28-3)13-17(27-2)14-20(21)29-4/h6-7,10,12-15H,5,8-9,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144195 (CHEMBL63585 | Dicyclopropylmethyl-[4-(2,4-dimethox...) Show SMILES CCCN(C(C1CC1)C1CC1)c1ncc(CC)c(n1)-c1ccc(OC)cc1OC Show InChI InChI=1S/C24H33N3O2/c1-5-13-27(23(17-7-8-17)18-9-10-18)24-25-15-16(6-2)22(26-24)20-12-11-19(28-3)14-21(20)29-4/h11-12,14-15,17-18,23H,5-10,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054239 (CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(n2)N2CCC=CC2)c(C)c1 |c:18| Show InChI InChI=1S/C18H23N5/c1-12-10-13(2)16(14(3)11-12)21-17-19-15(4)20-18(22-17)23-8-6-5-7-9-23/h5-6,10-11H,7-9H2,1-4H3,(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054219 (CHEMBL305671 | N-Benzyl-N-butyl-6-methyl-N'-(2,4,6...) Show SMILES CCCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C24H31N5/c1-6-7-13-29(16-21-11-9-8-10-12-21)24-26-20(5)25-23(28-24)27-22-18(3)14-17(2)15-19(22)4/h8-12,14-15H,6-7,13,16H2,1-5H3,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054255 (CHEMBL80806 | N-Cyclopropylmethyl-2-methyl-N-propy...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(C)cc(C)cc2C)nc(C)n1 Show InChI InChI=1S/C21H30N4/c1-6-9-25(13-18-7-8-18)20-12-19(22-17(5)23-20)24-21-15(3)10-14(2)11-16(21)4/h10-12,18H,6-9,13H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054223 (CHEMBL307871 | N-Benzyl-N-ethyl-6-methyl-N'-(2,4,6...) Show SMILES CCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-6-27(14-19-10-8-7-9-11-19)22-24-18(5)23-21(26-22)25-20-16(3)12-15(2)13-17(20)4/h7-13H,6,14H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054241 (6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)c(C)c1 Show InChI InChI=1S/C21H22F3N5/c1-12-9-13(2)18(14(3)10-12)28-20-27-15(4)26-19(29-20)25-11-16-5-7-17(8-6-16)21(22,23)24/h5-10H,11H2,1-4H3,(H2,25,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054238 (CHEMBL137434 | N-Benzyl-N'-(2,6-diethyl-phenyl)-N-...) Show SMILES CCN(Cc1ccccc1)c1nc(C)nc(Nc2c(CC)cccc2CC)n1 Show InChI InChI=1S/C23H29N5/c1-5-19-14-11-15-20(6-2)21(19)26-22-24-17(4)25-23(27-22)28(7-3)16-18-12-9-8-10-13-18/h8-15H,5-7,16H2,1-4H3,(H,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144198 (CHEMBL305583 | Propyl-(1-thiophen-3-yl-cyclopropyl...) Show SMILES CCCN(c1nccc(n1)-c1c(OC)cc(OC)cc1OC)C1(CC1)c1ccsc1 Show InChI InChI=1S/C23H27N3O3S/c1-5-11-26(23(8-9-23)16-7-12-30-15-16)22-24-10-6-18(25-22)21-19(28-3)13-17(27-2)14-20(21)29-4/h6-7,10,12-15H,5,8-9,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054234 (6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...) Show SMILES CN(CCc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-15-13-16(2)20(17(3)14-15)25-21-23-18(4)24-22(26-21)27(5)12-11-19-9-7-6-8-10-19/h6-10,13-14H,11-12H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50144189 (CHEMBL65979 | Cyclopentyl-propyl-[4-(2,4,6-trimeth...) Show SMILES CCCN(C1CCCC1)c1nccc(n1)-c1c(OC)cc(OC)cc1OC Show InChI InChI=1S/C21H29N3O3/c1-5-12-24(15-8-6-7-9-15)21-22-11-10-17(23-21)20-18(26-3)13-16(25-2)14-19(20)27-4/h10-11,13-15H,5-9,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]-CRF from CHO cells				Bioorg Med Chem Lett 14: 2083-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.053 BindingDB Entry DOI: 10.7270/Q2JH3KKJ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054222 (CHEMBL136519 | N,N-Diallyl-N'-(2,6-diethyl-phenyl)...) Show SMILES CCc1cccc(CC)c1Nc1nc(C)nc(n1)N(CC=C)CC=C Show InChI InChI=1S/C20H27N5/c1-6-13-25(14-7-2)20-22-15(5)21-19(24-20)23-18-16(8-3)11-10-12-17(18)9-4/h6-7,10-12H,1-2,8-9,13-14H2,3-5H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054229 (CHEMBL136828 | N-Cyclopropylmethyl-N'-(2,4-dimetho...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C19H27N5O2/c1-5-10-24(12-14-6-7-14)19-21-13(2)20-18(23-19)22-16-9-8-15(25-3)11-17(16)26-4/h8-9,11,14H,5-7,10,12H2,1-4H3,(H,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054254 (CHEMBL136593 | N-Cyclopropylmethyl-N-propyl-N'-(2,...) Show SMILES CCCN(CC1CC1)c1cc(Nc2c(Cl)cc(Cl)cc2Cl)ncn1 Show InChI InChI=1S/C17H19Cl3N4/c1-2-5-24(9-11-3-4-11)16-8-15(21-10-22-16)23-17-13(19)6-12(18)7-14(17)20/h6-8,10-11H,2-5,9H2,1H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054236 (6-Methyl-N-p-tolyl-N'-(4-trifluoromethyl-benzyl)-[...) Show SMILES Cc1ccc(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)cc1 Show InChI InChI=1S/C19H18F3N5/c1-12-3-9-16(10-4-12)26-18-25-13(2)24-17(27-18)23-11-14-5-7-15(8-6-14)19(20,21)22/h3-10H,11H2,1-2H3,(H2,23,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054224 (CHEMBL138124 | N,N-Diallyl-6-methyl-N'-p-tolyl-[1,...) Show SMILES Cc1ccc(Nc2nc(C)nc(n2)N(CC=C)CC=C)cc1 Show InChI InChI=1S/C17H21N5/c1-5-11-22(12-6-2)17-19-14(4)18-16(21-17)20-15-9-7-13(3)8-10-15/h5-10H,1-2,11-12H2,3-4H3,(H,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054231 (CHEMBL137291 | N-Benzyl-N'-(2,6-diethyl-phenyl)-6-...) Show SMILES CCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(CC)cccc2CC)n1 Show InChI InChI=1S/C24H31N5/c1-5-16-29(17-19-12-9-8-10-13-19)24-26-18(4)25-23(28-24)27-22-20(6-2)14-11-15-21(22)7-3/h8-15H,5-7,16-17H2,1-4H3,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054227 (CHEMBL136596 | N-Benzyl-N'-(2,6-dimethyl-phenyl)-6...) Show SMILES CCCN(Cc1ccccc1)c1nc(C)nc(Nc2c(C)cccc2C)n1 Show InChI InChI=1S/C22H27N5/c1-5-14-27(15-19-12-7-6-8-13-19)22-24-18(4)23-21(26-22)25-20-16(2)10-9-11-17(20)3/h6-13H,5,14-15H2,1-4H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054243 (CHEMBL343958 | N-Benzyl-N-ethyl-6-methyl-N'-p-toly...) Show SMILES CCN(Cc1ccccc1)c1nc(C)nc(Nc2ccc(C)cc2)n1 Show InChI InChI=1S/C20H23N5/c1-4-25(14-17-8-6-5-7-9-17)20-22-16(3)21-19(24-20)23-18-12-10-15(2)11-13-18/h5-13H,4,14H2,1-3H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054233 (CHEMBL343704 | N-Cyclopropylmethyl-N'-(2,6-diethyl...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(CC)cccc2CC)n1 Show InChI InChI=1S/C21H31N5/c1-5-13-26(14-16-11-12-16)21-23-15(4)22-20(25-21)24-19-17(6-2)9-8-10-18(19)7-3/h8-10,16H,5-7,11-14H2,1-4H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054220 (CHEMBL135615 | N-Cyclopropylmethyl-6-methyl-N-prop...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2ccc(C)cc2)n1 Show InChI InChI=1S/C18H25N5/c1-4-11-23(12-15-7-8-15)18-20-14(3)19-17(22-18)21-16-9-5-13(2)6-10-16/h5-6,9-10,15H,4,7-8,11-12H2,1-3H3,(H,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054251 (CHEMBL138687 | N*2*-Cyclopropylmethyl-6-methyl-N*2...) Show SMILES CCCN(CC1CC1)c1nc(C)cc(Nc2c(Cl)cc(Cl)cc2Cl)n1 Show InChI InChI=1S/C18H21Cl3N4/c1-3-6-25(10-12-4-5-12)18-22-11(2)7-16(24-18)23-17-14(20)8-13(19)9-15(17)21/h7-9,12H,3-6,10H2,1-2H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human Corticotropin releasing factor receptor 1 tested at 6-12 doses				J Med Chem 39: 4358-60 (1996) Article DOI: 10.1021/jm960149e BindingDB Entry DOI: 10.7270/Q29022V6
					More data for this Ligand-Target Pair

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