Reaction Details |
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Target | Peptide deformylase |
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Ligand | BDBM50089215 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_154575 (CHEMBL761923) |
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IC50 | 94±n/a nM |
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Citation | Apfel, C; Banner, DW; Bur, D; Dietz, M; Hirata, T; Hubschwerlen, C; Locher, H; Page, MG; Pirson, W; Rossé, G; Specklin, JL Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents. J Med Chem43:2324-31 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Peptide deformylase |
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Name: | Peptide deformylase |
Synonyms: | 3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2 |
Type: | n/a |
Mol. Mass.: | 16901.39 |
Organism: | Escherichia coli |
Description: | n/a |
Residue: | 150 |
Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIGLRLGNGKYCTLRLFFNQV
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BDBM50089215 |
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n/a |
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Name | BDBM50089215 |
Synonyms: | 3-(3-Methoxy-benzenesulfinyl)-heptanoic acid hydroxyamide | CHEMBL77578 |
Type | Small organic molecule |
Emp. Form. | C14H21NO4S |
Mol. Mass. | 299.386 |
SMILES | CCCCC(CC(=O)NO)S(=O)c1cccc(OC)c1 |
Structure |
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