| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50419409 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_785558 (CHEMBL1920205) |
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| IC50 | 25.12±n/a nM |
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| Citation |  Allan, AC; Billinton, A; Brown, SH; Chowdhury, A; Eatherton, AJ; Fieldhouse, C; Giblin, GM; Goldsmith, P; Hall, A; Hurst, DN; Naylor, A; Rawlings, DA; Sime, M; Scoccitti, T; Theobald, PJ Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists. Bioorg Med Chem Lett21:4343-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50419409 |
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| n/a |
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| Name | BDBM50419409 |
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| Synonyms: | CHEMBL1915263 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19ClF3N3O3 |
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| Mol. Mass. | 477.863 |
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| SMILES | Cc1cc(nn1Cc1cc(Cl)cc2cc(oc12)-c1ccccc1)C(=O)NCC(O)C(F)(F)F |
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| Structure | 
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