| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM50156529 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1570609 (CHEMBL3794977) |
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| EC50 | >10000±n/a nM |
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| Citation |  Ogawa, S; Watanabe, T; Moriyuki, K; Goto, Y; Yamane, S; Watanabe, A; Tsuboi, K; Kinoshita, A; Okada, T; Takeda, H; Tani, K; Maruyama, T Structural optimization and structure-functional selectivity relationship studies of G protein-biased EP2 receptor agonists. Bioorg Med Chem Lett26:2446-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 43335.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43115 |
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| Residue: | 390 |
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| Sequence: | MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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| BDBM50156529 |
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| n/a |
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| Name | BDBM50156529 |
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| Synonyms: | CHEMBL3794226 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClO6 |
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| Mol. Mass. | 406.857 |
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| SMILES | [H][C@]12C[C@@H](O)[C@H](COc3ccc(Cl)c(C)c3)[C@@]1([H])CC[C@@H](O2)c1ccc(o1)C(O)=O |r| |
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| Structure | 
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