| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
|---|
| Ligand | BDBM50156542 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1578425 (CHEMBL3808242) |
|---|
| EC50 | 3.9±n/a nM |
|---|
| Citation |  Ogawa, S; Watanabe, T; Sugimoto, I; Moriyuki, K; Goto, Y; Yamane, S; Watanabe, A; Tsuboi, K; Kinoshita, A; Kigoshi, H; Tani, K; Maruyama, T Discovery of G Protein-Biased EP2 Receptor Agonists. ACS Med Chem Lett7:306-11 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP2 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP2 subtype |
|---|
| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39775.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43116 |
|---|
| Residue: | 358 |
|---|
| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
|
|
|
|---|
| BDBM50156542 |
|---|
| n/a |
|---|
| Name | BDBM50156542 |
|---|
| Synonyms: | CHEMBL3793786 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20ClNO5S |
|---|
| Mol. Mass. | 409.884 |
|---|
| SMILES | [H][C@]12C[C@@H](O)[C@H](COc3ccc(Cl)cc3)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
