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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM199158 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Competitive Binding Assays | ||
| Ki | 34.40±0.0 nM | ||
| Citation |  Li, W; Zhang, L; Xu, L; Yuan, C; Du, P; Chen, J; Zhen, X; Fu, W Functional reversal of (-)-Stepholidine analogues by replacement of benzazepine substructure using the ring-expansion strategy. Chem Biol Drug Des88:599-607 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
| ||
| BDBM199158 | |||
| n/a | |||
| Name | BDBM199158 | ||
| Synonyms: | 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((+)-15e) | 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol ((-)-15e) | 3,11-dimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4,5]azepino[2,1-a]isoquinoline-2,10-diol (15e) | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23NO4 | ||
| Mol. Mass. | 341.4009 | ||
| SMILES | COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4O | ||
| Structure | 
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