| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM232204 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | [3H]8-OH-DPAT Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 300.15±n/a K |
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| IC50 | 7.6e+3±n/a nM |
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| Comments | extracted |
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| Citation |  Jung, JC; Min, D; Kim, H; Jang, S; Lee, Y; Park, W; Khan, IA; Moon, HI; Jung, M; Oh, S Design, synthesis, and biological evaluation of 3,4,5-trimethoxyphenyl acrylamides as antinarcotic agents. J Enzyme Inhib Med Chem25:38-43 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM232204 |
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| n/a |
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| Name | BDBM232204 |
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| Synonyms: | 3,4,5-Trimethoxycinnamic acid (TMCA) |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14O5 |
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| Mol. Mass. | 238.2366 |
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| SMILES | COc1cc(\C=C\C(O)=O)cc(OC)c1OC |
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| Structure | 
|
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