| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 11B1, mitochondrial |
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| Ligand | BDBM233867 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cellular Enzyme Assay |
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| Temperature | 310.15±n/a K |
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| EC50 | 449.9±n/a nM |
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| Comments | extracted |
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| Citation |  Aebi, J; Amrein, K; Fantasia, SM; Hornsperger, B; Kuhn, B; Liu, Y; Maerki, HP; Mayweg, AV; Mohr, P; Scalone, M; Tan, X; Zhou, M Bicyclic dihydroquinoline-2-one derivatives US Patent US9353081 Publication Date 5/31/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 11B1, mitochondrial |
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| Name: | Cytochrome P450 11B1, mitochondrial |
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| Synonyms: | C11B1_HUMAN | CYP11B1 | CYPXIB1 | Cytochrome P450 11B, mitochondrial precursor | Cytochrome P450 11B1 | Cytochrome P450 11B1 (CYP11B1) | Cytochrome P450 11B1, mitochondrial | S11BH |
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| Type: | Enzyme |
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| Mol. Mass.: | 57591.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15538 |
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| Residue: | 503 |
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| Sequence: | MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQG
YEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR
QHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNA
RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS
PDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATT
ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRP
ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQED
IKMVYSFILRPSMFPLLTFRAIN
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| BDBM233867 |
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| n/a |
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| Name | BDBM233867 |
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| Synonyms: | US9353081, 61 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N3O |
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| Mol. Mass. | 307.3895 |
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| SMILES | CN1C(=O)CCc2cc(ccc12)-c1cncc2[C@H](N)CCCc12 |r| |
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| Structure | 
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