Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 3A | ||
| Ligand | BDBM322362 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | [3H]BRL 43694 Competition Binding (h-5HT3 Assay | ||
| Ki | 170±n/a nM | ||
| Citation |  Acharya, R; Burnett, DA; Bursavich, MG; Cook, AS; Harrison, BA; Koenig, G; Mcriner, AJ Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors US Patent US10183938 Publication Date 1/22/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 3A | |||
| Name: | 5-hydroxytryptamine receptor 3A | ||
| Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
| Type: | Protein | ||
| Mol. Mass.: | 55283.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P46098 | ||
| Residue: | 478 | ||
| Sequence: |
| ||
| BDBM322362 | |||
| n/a | |||
| Name | BDBM322362 | ||
| Synonyms: | (R)-N-(2,2-dimethylquinuclidin-3-yl)-7-methylbenzo[b]thiophene-2-carboxamide | US10183938, Compound (R)-126 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H24N2OS | ||
| Mol. Mass. | 328.472 | ||
| SMILES | Cc1cccc2cc(sc12)C(=O)N[C@@H]1C2CCN(CC2)C1(C)C |wD:13.14,(-4.65,2.31,;-4.65,.77,;-5.98,,;-5.98,-1.54,;-4.65,-2.31,;-3.32,-1.54,;-1.85,-2.02,;-.95,-.77,;-1.85,.48,;-3.32,,;.59,-.77,;1.36,-2.1,;1.36,.56,;2.9,.56,;3.67,1.9,;4.71,1.38,;5.28,.38,;5.21,-.77,;5.98,.56,;5.21,1.9,;3.67,-.77,;3.67,-2.31,;2.34,-1.54,)| | ||
| Structure | 
| ||