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TargetAndrogen Receptor
LigandBDBM354712
Substrate/Competitorn/a
Meas. Tech.Binding Assay
IC50 8.50±n/a nM
Citation Choi SPChoi SMSon BHKim HJKim JMJang BJSung JHLee JHKim EKang KKKim S Oxazolidine-based compound and selective androgen receptor agonist comprising same US Patent  US9809583 Publication Date 11/7/2017
More Info.:Get all data from this article,  Assay Method
 
Androgen Receptor
Name:Androgen Receptor
Synonyms:n/a
Type:n/a
Mol. Mass.:97086.15
Organism:Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Description:A0A0D9RHK8
Residue:900
Sequence:
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLQQQQQQ
QQQQQQQQETSPRQQQKQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVP
EPGAAVAAGKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQL
LQQQQQEAVSEGSSNGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEA
LEHLSPGEQLRGDCMYAPVLGVPPGVRPIPCAPLAECKGSLLDDSAGKSTEDTVEYSPFK
GGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAG
PPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASS
SWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGAGEAGAVAPYGYTRPPQGLAGQEGDFTAP
DVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTC
LICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKC
YEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETAQKLTVSHIEGYECQPIFLNVLEA
IEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQY
SWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQI
TPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQL
TKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
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  Blast E-value cutoff:
BDBM354712
n/a
NameBDBM354712
Synonyms:Preparation of N-(4-(((2R,5S)-3-(4-cyano-3-(trifluoromethyl)phenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methoxy)phenyl)acetamide | US9809583, Example 25
TypeSmall organic molecule
Emp. Form.C21H17F6N3O3
Mol. Mass.473.3684
SMILESCC(=O)Nc1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)cc1 |r|
Structure
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