| Reaction Details |
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 | Report a problem with these data |
| Target | D-alanine--D-alanyl carrier protein ligase |
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| Ligand | BDBM392793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | in vitro DltA activity assay |
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| IC50 | 36.0±n/a nM |
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| Citation |  Atamanyuk, D; Chevreuil, F; Faivre, F; Lecointe, N; Ledoussal, B; Oliveira, C; Simon, C; Gerusz, V Heteroaromatic derivatives and their use as pharmaceuticals US Patent US10301305 Publication Date 5/28/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| D-alanine--D-alanyl carrier protein ligase |
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| Name: | D-alanine--D-alanyl carrier protein ligase |
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| Synonyms: | D-alanine--poly(phosphoribitol) ligase subunit 1 | DAE | DCL | dltA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56736.38 |
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| Organism: | Enterococcus faecium E1679 |
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| Description: | Q3XZT7 |
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| Residue: | 504 |
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| Sequence: | MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYYLEKKVEGDGPIVVFGN
LEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSMVISIGDWIEDIPSVPVIT
KKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKGVQISHDNLVSFVQWTMEDFG
IKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKAVVQDFRQLFATLPALKLNVWVS
TPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKTAESLLDRFPNARIYNTYGPTEATV
AISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQEGKPVSKGETGEIIIAGPSVSKGYLNN
PEKTAAAFFCQNDLASYHTGDAGRLDEYGLLFYEGRMDQQVKLHGYRIELGDIEHYLLQD
NRIKQAVVVPKYQGTKVQQLVAFVVLENKTKQPDFQLTKSIKEQLLEVVMDYMIPQKFHY
VDLLPQTVNGKIDRKKLTAEVNPE
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| BDBM392793 |
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| n/a |
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| Name | BDBM392793 |
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| Synonyms: | 7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-3H-benzimidazole-4-carboxamide methanesulfonic acid salt | US10301305, Example 210 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25N5O3 |
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| Mol. Mass. | 407.4656 |
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| SMILES | CN1CCC[C@@H]1COc1cc(-c2cnc3OCCCc3c2)c2nc[nH]c2c1C(N)=O |r| |
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| Structure | 
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