| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM81550 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| Kd | 13±0.0 nM |
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| Citation |  Miduturu, CV; Deng, X; Kwiatkowski, N; Yang, W; Brault, L; Filippakopoulos, P; Chung, E; Yang, Q; Schwaller, J; Knapp, S; King, RW; Lee, JD; Herrgard, S; Zarrinkar, P; Gray, NS High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors. Chem Biol18:868-79 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
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| BDBM81550 |
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| n/a |
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| Name | BDBM81550 |
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| Synonyms: | Furan thiazolidinediones, A47 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11N3O2S |
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| Mol. Mass. | 321.353 |
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| SMILES | N=C1NC(=O)\C(S1)=C/c1ccc(o1)-c1cncc2ccccc12 |
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| Structure | 
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