| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 4 |
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| Ligand | BDBM50242266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1671400 (CHEMBL4021429) |
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| IC50 | 217±n/a nM |
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| Citation |  Sattigeri, JA; Sethi, S; Davis, JA; Ahmed, S; Rayasam, GV; Jadhav, BG; Chilla, SM; Datta, D; Gadhave, A; Tulasi, VK; Jain, T; Voleti, S; Benjamin, B; Udupa, S; Jain, G; Singh, Y; Srinivas, K; Bansal, VS; Ray, A; Bhatnagar, PK; Cliffe, IA Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome. Bioorg Med Chem Lett27:2313-2318 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 4 |
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| Name: | Dipeptidyl peptidase 4 |
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| Synonyms: | Cd26 | DPP4_MOUSE | Dipeptidyl peptidase IV | Dpp4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 87433.73 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1335112 |
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| Residue: | 760 |
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| Sequence: | MKTPWKVLLGLLGVAALVTIITVPIVLLSKDEAAADSRRTYSLADYLKSTFRVKSYSLWW
VSDFEYLYKQENNILLLNAEHGNSSIFLENSTFESFGYHSVSPDRLFVLLEYNYVKQWRH
SYTASYNIYDVNKRQLITEEKIPNNTQWITWSPEGHKLAYVWKNDIYVKVEPHLPSHRIT
STGEENVIYNGITDWVYEEEVFGAYSALWWSPNNTFLAYAQFNDTGVPLIEYSFYSDESL
QYPKTVWIPYPKAGAVNPTVKFFIVNIDSLSSSSSAAPIQIPAPASVARGDHYLCDVVWA
TEERISLQWLRRIQNYSVMAICDYDKINLTWNCPSEQQHVEMSTTGWVGRFRPAEPHFTS
DGSSFYKIISDKDGYKHICHFPKDKKDCTFITKGAWEVISIEALTSDYLYYISNQYKEMP
GGRNLYKIQLTDHTNVKCLSCDLNPERCQYYAVSFSKEAKYYQLGCWGPGLPLYTLHRST
DHKELRVLEDNSALDRMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLLDV
YAGPCSQKADASFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTLEVEDQ
IEAARQFVKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVY
TERYMGLPIPEDNLDHYRNSTVMSRAEHFKQVEYLLIHGTADDNVHFQQSAQISKALVDA
GVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLH
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| BDBM50242266 |
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| n/a |
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| Name | BDBM50242266 |
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| Synonyms: | CHEMBL4067185 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H33F3N4O6 |
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| Mol. Mass. | 578.58 |
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| SMILES | C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1C[C@H](C[C@H]1C(O)=O)NC(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| |
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| Structure | 
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