| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain testis-specific protein |
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| Ligand | BDBM50251045 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1682918 |
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| IC50 | >100000±n/a nM |
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| Citation |  Ouyang, L; Zhang, L; Liu, J; Fu, L; Yao, D; Zhao, Y; Zhang, S; Wang, G; He, G; Liu, B Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer. J Med Chem60:9990-10012 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain testis-specific protein |
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| Name: | Bromodomain testis-specific protein |
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| Synonyms: | BRDT | BRDT_HUMAN | Bromodomain and extra-terminal motif (BET) | CT9 | Cancer/testis antigen 9 | RING3-like protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 107982.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502985 |
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| Residue: | 947 |
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| Sequence: | MSLPSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVK
LQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQ
ALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV
FPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSV
ALPPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVD
VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVT
MARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERV
KRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRL
KEKSKRNQPKKRKQQFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSR
EPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQ
ELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSS
DSSDSESEMFPKFTEVKPNDSPSKENVKKMKNECIPPEGRTGVTQIGYCVQDTTSANTTL
VHQTTPSHVMPPNHHQLAFNYQELEHLQTVKNISPLQILPPSGDSEQLSNGITVMHPSGD
SDTTMLESECQAPVQKDIKIKNADSWKSLGKPVKPSGVMKSSDELFNQFRKAAIEKEVKA
RTQELIRKHLEQNTKELKASQENQRDLGNGLTVESFSNKIQNKCSGEEQKEHQQSSEAQD
KSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQSDIMTMFENNFD
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| BDBM50251045 |
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| n/a |
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| Name | BDBM50251045 |
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| Synonyms: | CHEMBL4077274 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N3O2S |
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| Mol. Mass. | 341.427 |
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| SMILES | CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(O)c(C)c1 |
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| Structure | 
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