| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50011544 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_47674 |
|---|
| IC50 | 23.0±n/a nM |
|---|
| Citation |  Tilley, JW; Danho, W; Lovey, K; Wagner, R; Swistok, J; Makofske, R; Michalewsky, J; Triscari, J; Nelson, D; Weatherford, S Carboxylic acids and tetrazoles as isosteric replacements for sulfate in cholecystokinin analogues. J Med Chem34:1125-36 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | CCKBR | Cholecystokinin B receptor | GASR_BOVIN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48807.54 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_48437 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MELLKPNRSVLGSGPGPGASLCRSGGPLLNGSGTGNLSCEPPRIRGAGTRELELAIRVTL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVVCKAVSYFMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWM
LSGLLMVPYPVYTAVQPAGPRVLQCMHRWPSARVRQTWSVLLLLLLFFVPGVVMAVAYGL
ISRELYLGLRFDGDSDSESQSRVGSQGGLPGGTGQGPAQANGRCRSETRLAGEDGDGCYV
QLPRSRPALEMSALTAPTPGPGSGTRPAQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSAN
TWRAFDGPGAHRALSGAPISFIHLLTYASACVNPLVYCFMHRRFRQACLDTCTRCCPRPP
RARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50011544 |
|---|
| n/a |
|---|
| Name | BDBM50011544 |
|---|
| Synonyms: | Ac-(R,S)Phe(3-CH2COOH)-Met-Gly-Trp-Met-Asp-Phe-NH2 | CHEMBL2370119 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C49H61N9O12S2 |
|---|
| Mol. Mass. | 1032.192 |
|---|
| SMILES | CSCC[C@H](NC(=O)C(Cc1cccc(CC(O)=O)c1)NC(C)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
