| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50020655 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_215034 (CHEMBL820884) |
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| Ki | 4.60±n/a nM |
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| Citation |  Huffman, WF; Ali, FE; Bryan, WM; Callahan, JF; Moore, ML; Silvestri, JS; Yim, NC; Kinter, LB; McDonald, JE; Ashton-Shue, D Novel vasopressin analogues that help define a minimum effective antagonist pharmacophore. J Med Chem28:1759-60 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR2 | V2R_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40556.17 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_214870 |
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| Residue: | 370 |
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| Sequence: | MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGA
LVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMV
GMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQR
DVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPA
ERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATA
SSFSARDTSS
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| BDBM50020655 |
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| n/a |
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| Name | BDBM50020655 |
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| Synonyms: | CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-10-(2-carbamoyl-ethyl)-7-carbamoylmethyl-16-(4-hydroxy-benzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carbonyl]-pyrrolidine-2-carbonyl}-amino)-hexanoylamino]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C46H64N12O13S2 |
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| Mol. Mass. | 1057.203 |
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| SMILES | NCCCC[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(O)=O |
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| Structure | 
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