Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016752 (CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016752 (CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016760 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016756 (CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016753 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016753 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016757 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016757 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020655 (CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of hog kidney renin | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020655 (CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016747 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016747 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016760 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016760 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016756 (CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020653 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016755 (20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016755 (20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016763 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50016763 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016754 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020656 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020656 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016761 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016750 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016762 (20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020654 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020653 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020654 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020651 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020651 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029108 (6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016760 (19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016749 (20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016746 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016759 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029102 (7-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020652 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50020652 (1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney. | J Med Chem 28: 1759-60 (1986) BindingDB Entry DOI: 10.7270/Q2CC0ZNX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029107 (8-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016748 (1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029101 (5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029099 (5,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016758 (2-[20-Benzyl-23-(4-ethoxy-benzyl)-11-(2-hydroxy-py...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Sus scrofa) | BDBM50016751 (20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Smith Kline & French Laboratories Curated by ChEMBL | Assay Description Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor) | J Med Chem 32: 391-6 (1989) BindingDB Entry DOI: 10.7270/Q2GM8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM13014 (7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029108 (6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029102 (7-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potency | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50029101 (5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase | J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |
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