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TargetHLA class I histocompatibility antigen, A alpha chain
LigandBDBM4851
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1778180 (CHEMBL4235172)
Kd 21200±n/a nM
Citation Ren, JDsouza, NRDeng, HLee, HBouvier, MJohnson, ME Discovery of small molecule inhibitors of adenovirus by disrupting E3-19K/HLA-A2 interactions. Bioorg Med Chem Lett28:2837-2841 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HLA class I histocompatibility antigen, A alpha chain
Name:HLA class I histocompatibility antigen, A alpha chain
Synonyms:HLA class I histocompatibility antigen A-3 | HLA class I histocompatibility antigen, A-3 alpha chain | HLA-A | HLAA | HLAA_HUMAN | MHC class I antigen A*3
Type:PROTEIN
Mol. Mass.:40836.72
Organism:Homo sapiens (Human)
Description:ChEMBL_47858
Residue:365
Sequence:
MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
DSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQ
IMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQL
RAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLT
WQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEL
SSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSL
TACKV
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BDBM4851
n/a
NameBDBM4851
Synonyms:(4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine | (A) PTK787 | CGP 79787 | CHEMBL101253 | CHEMBL75232 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine | PTK-787 | PTK787 | ZK222584 | cid_151194
TypeSmall organic molecule
Emp. Form.C20H15ClN4
Mol. Mass.346.813
SMILESClc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: