| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-mannosidase |
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| Ligand | BDBM50016703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32498 (CHEMBL641375) |
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| IC50 | 110000±n/a nM |
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| Citation |  Asano, N; Kizu, H; Oseki, K; Tomioka, E; Matsui, K; Okamoto, M; Baba, M N-alkylated nitrogen-in-the-ring sugars: conformational basis of inhibition of glycosidases and HIV-1 replication. J Med Chem38:2349-56 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-mannosidase |
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| Name: | Alpha-mannosidase |
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| Synonyms: | Mannosidase 2, alpha B1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 114350.15 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_32498 |
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| Residue: | 1009 |
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| Sequence: | MGTGSLAPGVRAGGGNTGWLWMSSCNLGLPVLSISFLIWLLLAAPGAQAAGYKTCPTTKP
GMLNVHLLPHTHDDVGWLKTVDQYYYGIMSDVQHASVQYILDSVIYSLLNDPTRRFIYVE
MAFFSRWWKQQTNVTQDAVRNLVRQGRLEFVNGGWVMNDEAATHYGAIVDQMTLGLRFLQ
DTFGSDGLPRVAWHIDPFGHSREQASLFAQMGFDGFFLGRIDYQDKFNRKRKLKMEELWR
ASASLKPPAADLFTGVLPNNYNPPKDLCWDVLCTDPPVVDDPTSPEFNANKLVDYFLNLA
SSQKKYYRTNHTVMTMGSDFQYENANMWFKNMDKLIRLVNEQQANGSKVHVLYSTPSCYL
WELNKANLTWTVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
PEAKVGPYGSGDSAPLNEAMAVLQHHDAVTGTARQNVVNDYAKQLAAGWGPCEVLVSNAL
ARLSLYKQNFSFCREINISICPASQTSEHFRVIIYNPVGRKVDLMVRLPVSEGIFLVKDP
NDRRISSNVVMVPSAYSKTYQWELLFPASVPALGFSIYSVNKMSGHNHQAHNLTARPKKS
KSRVLVIENKYIRATFDSDTGLLRKIENLEQNISLPVRQGFFWYNASAGDEESPQASGAY
IFRPSHRKPLPVSHWAQVTLVKTNLVQEVHQNFSAWCSQVIRLYEGQRHLELEWTVGPIP
VKDDWGKEVISRFNTPMRTRGQFFTDSNGREILKRRDDFRPTWTLNQTEPVAGNYYPVNT
RIYITDGHMQLTVLTDRSQGGSSLLDGSLELMVHRRLLVDDERGVAEPLLETDTGDKVRG
RHLVILSSVSDAAARHRLLAEQEVLAPQVVLAHGGSSPYHSQAPKMQFSALRRELPPQVH
LLTLARWGPKMLLLRLEHQFAVKEDSNRNLSSPVTLNLQNLFKTFTINYLQETTLAANQP
LSRVSRLKWMTDTGPISYPAPSRLDPTSITLQPMQIRTFLASVQWQRLI
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| BDBM50016703 |
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| n/a |
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| Name | BDBM50016703 |
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| Synonyms: | 2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM50031485 | CHEMBL80254 | Imino-D-Arabinitol |
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| Type | Small organic molecule |
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| Emp. Form. | C5H11NO3 |
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| Mol. Mass. | 133.1457 |
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| SMILES | OC[C@H]1NC[C@@H](O)[C@@H]1O |r| |
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| Structure | 
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