| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50033651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_136067 |
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| IC50 | 1.5±n/a nM |
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| Citation |  Sebastian, A; Bidlack, JM; Jiang, Q; Deecher, D; Teitler, M; Glick, SD; Archer, S 14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity. J Med Chem36:3154-60 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45038.37 |
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| Organism: | CALF |
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| Description: | OPIATE Mu 2 0 CALF::P79350 |
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| Residue: | 401 |
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| Sequence: | MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLC
PSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALA
TSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALD
LRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVF
IFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIH
IYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSST
IEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
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| BDBM50033651 |
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| n/a |
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| Name | BDBM50033651 |
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| Synonyms: | 1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-17-yl]-4-(4-nitrophenyl)-(Z)-2-butenamide | CHEMBL110238 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H23N3O6 |
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| Mol. Mass. | 473.4773 |
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| SMILES | CN1CCC23[C@H]4Oc5c2c(CC1[C@]3(NC(=O)C=Cc1ccc(cc1)[N+]([O-])=O)C=CC4=O)ccc5O |w:17.20,c:31,TLB:13:12:8.9.10:1.3.2,THB:0:1:12:8.9.10,7:8:12:1.3.2| |
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| Structure | 
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