| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50299109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_955713 (CHEMBL2379023) |
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| EC50 | 600±n/a nM |
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| Citation |  Carrieri, A; Giudici, M; Parente, M; De Rosas, M; Piemontese, L; Fracchiolla, G; Laghezza, A; Tortorella, P; Carbonara, G; Lavecchia, A; Gilardi, F; Crestani, M; Loiodice, F Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors ?/? agonists. Eur J Med Chem63:321-32 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
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| Type: | Nuclear Receptor |
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| Mol. Mass.: | 57613.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37231 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50299109 |
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| n/a |
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| Name | BDBM50299109 |
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| Synonyms: | (2S)-2-(4-benzylphenoxy)-3-phenylpropanoic acid | (S)-2-(4-Benzyl-phenoxy)-3-phenyl-propanoic Acid | (S)-2-(4-benzylphenoxy)-3-phenylpropanoic acid | CHEMBL489074 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20O3 |
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| Mol. Mass. | 332.3924 |
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| SMILES | OC(=O)[C@H](Cc1ccccc1)Oc1ccc(Cc2ccccc2)cc1 |r| |
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| Structure | 
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