Compile Data Set for Download or QSAR

Found 1134 hits with Last Name = 'loiodice' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128107 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50128107 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50128110 (1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...) Show SMILES CC1CCN(CCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C14H20ClNO/c1-12-6-8-16(9-7-12)10-11-17-14-4-2-13(15)3-5-14/h2-5,12H,6-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128110 (1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...) Show SMILES CC1CCN(CCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C14H20ClNO/c1-12-6-8-16(9-7-12)10-11-17-14-4-2-13(15)3-5-14/h2-5,12H,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128111 (1-((2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dieny...) Show SMILES C(\C=C\C=C\c1ccc2OCOc2c1)N1CCCCC1 Show InChI InChI=1S/C17H21NO2/c1(4-10-18-11-5-2-6-12-18)3-7-15-8-9-16-17(13-15)20-14-19-16/h1,3-4,7-9,13H,2,5-6,10-12,14H2/b4-1+,7-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585434 (CHEMBL5093782) Show SMILES Cl.COc1ccc(OCCN2CCC(C)CC2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128104 (1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...) Show SMILES C[C@H](COc1ccc(Cl)cc1)CN1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-9-18(10-8-13)11-14(2)12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.09	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128108 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50128108 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585435 (CHEMBL5083713) Show SMILES Cl.COc1ccc(OC[C@@H](C)N2CCC(C)CC2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128113 (1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...) Show SMILES C[C@H](CCN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)12-9-14(2)19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585436 (CHEMBL5080230) Show SMILES Cl.COc1ccc(OC[C@H](C)N2CCC(C)CC2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128101 (1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)CN1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-9-18(10-8-13)11-14(2)12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128112 (1-[3-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES CC1CCN(CCCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C15H22ClNO/c1-13-7-10-17(11-8-13)9-2-12-18-15-5-3-14(16)4-6-15/h3-6,13H,2,7-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128105 (1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES C[C@H](CN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)11-13(2)18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128109 (1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...) Show SMILES C[C@@H](CCN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)12-9-14(2)19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128103 (1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...) Show SMILES C[C@H](CCOc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)14(2)9-12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50084012 ((3,4-Dichloro-phenyl)-acetic acid 2-pyrrolidin-1-y...) Show SMILES Clc1ccc(CC(=O)OCCN2CCCC2)cc1Cl Show InChI InChI=1S/C14H17Cl2NO2/c15-12-4-3-11(9-13(12)16)10-14(18)19-8-7-17-5-1-2-6-17/h3-4,9H,1-2,5-8,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128106 (1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...) Show SMILES C[C@@H](CCOc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)14(2)9-12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) Show SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair				3D Structure (crystal)
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128105 (1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES C[C@H](CN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)11-13(2)18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128110 (1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...) Show SMILES CC1CCN(CCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C14H20ClNO/c1-12-6-8-16(9-7-12)10-11-17-14-4-2-13(15)3-5-14/h2-5,12H,6-11H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128107 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50001028 ((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...) Show SMILES [#6]-[#6@H]1-[#6@H]-2-[#6]-c3ccc(-[#8])cc3[C@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |r,TLB:16:15:1:3.4.10| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585431 (CHEMBL5082024) Show SMILES Cl.C[C@H]1CCC[C@@H](C)N1CCCOc1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128103 (1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...) Show SMILES C[C@H](CCOc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)14(2)9-12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128112 (1-[3-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES CC1CCN(CCCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C15H22ClNO/c1-13-7-10-17(11-8-13)9-2-12-18-15-5-3-14(16)4-6-15/h3-6,13H,2,7-12H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128109 (1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...) Show SMILES C[C@@H](CCN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)12-9-14(2)19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128102 (1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES C[C@@H](CN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)11-13(2)18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128104 (1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...) Show SMILES C[C@H](COc1ccc(Cl)cc1)CN1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-9-18(10-8-13)11-14(2)12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585430 (CHEMBL5094446) Show SMILES Cl.C[C@H]1CCCCN1CCOc1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50585431 (CHEMBL5082024) Show SMILES Cl.C[C@H]1CCC[C@@H](C)N1CCCOc1ccc(Cl)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128101 (1-[3-(4-Chloro-phenoxy)-2-methyl-propyl]-4-methyl-...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)CN1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-9-18(10-8-13)11-14(2)12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585429 (CHEMBL5087328) Show SMILES Cl.C[C@@H]1CCCCN1CCOc1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585439 (CHEMBL5089619) Show SMILES Cl.COc1ccc(OCCCN2[C@@H](C)CCC[C@H]2C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128108 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50062551 (CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572) Show SMILES [H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N1[C@H](C)CCO2 |r| Show InChI InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128113 (1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine...) Show SMILES C[C@H](CCN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)12-9-14(2)19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128102 (1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) Show SMILES C[C@@H](CN1CCC(C)CC1)Oc1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)11-13(2)18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585437 (CHEMBL5090648) Show SMILES Cl.COc1ccc(OCCN2CCCC[C@H]2C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus)	BDBM50128106 (1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-...) Show SMILES C[C@@H](CCOc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C16H24ClNO/c1-13-7-10-18(11-8-13)14(2)9-12-19-16-5-3-15(17)4-6-16/h3-6,13-14H,7-12H2,1-2H3/t14-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585438 (CHEMBL5090805) Show SMILES Cl.COc1ccc(OCCN2CCCC[C@@H]2C)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50128108 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI InChI=1S/C15H22ClNO/c1-12-7-9-17(10-8-12)13(2)11-18-15-5-3-14(16)4-6-15/h3-6,12-13H,7-11H2,1-2H3/t13-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50585439 (CHEMBL5089619) Show SMILES Cl.COc1ccc(OCCCN2[C@@H](C)CCC[C@H]2C)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50585432 (CHEMBL5084203) Show SMILES Cl.C[C@H]1CCC[C@@H](C)N1CCOc1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50585430 (CHEMBL5094446) Show SMILES Cl.C[C@H]1CCCCN1CCOc1ccc(Cl)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1 Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	74	-40.3	n/a	n/a	n/a	n/a	n/a	7.5	22
Consiglio Nazionale delle Ricerche					Assay Description The scintillation proximity assay was performed in 96-well plates containing polylysine-coated yttrium silicate beads, His-PPARgamma-LBD, and [3H]ros...				J Biol Chem 282: 17314-24 (2007) Article DOI: 10.1074/jbc.M702316200 BindingDB Entry DOI: 10.7270/Q27M0682
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1 Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Tumori"Giovanni Paolo II" Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...				J Med Chem 55: 37-54 (2012) Article DOI: 10.1021/jm201306q BindingDB Entry DOI: 10.7270/Q23N24JP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50585429 (CHEMBL5087328) Show SMILES Cl.C[C@@H]1CCCCN1CCOc1ccc(Cl)cc1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membranes measured after 120 mins by scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.114038 BindingDB Entry DOI: 10.7270/Q2K35ZJK
					More data for this Ligand-Target Pair

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