| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM37340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1276214 (CHEMBL3089537) |
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| EC50 | 7870±n/a nM |
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| Citation |  Guerrero, M; Poddutoori, R; Urbano, M; Peng, X; Spicer, TP; Chase, PS; Hodder, PS; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist. Bioorg Med Chem Lett23:6346-9 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM37340 |
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| n/a |
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| Name | BDBM37340 |
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| Synonyms: | MLS000116372 | N,N-dicyclohexyl-5-propyl-1,2-oxazole-3-carboxamide | N,N-dicyclohexyl-5-propyl-3-isoxazolecarboxamide | N,N-dicyclohexyl-5-propyl-isoxazole-3-carboxamide | SMR000093349 | cid_5309153 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N2O2 |
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| Mol. Mass. | 318.4537 |
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| SMILES | CCCc1cc(no1)C(=O)N(C1CCCCC1)C1CCCCC1 |
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| Structure | 
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