| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
|---|
| Ligand | BDBM37340 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1276213 (CHEMBL3089536) |
|---|
| EC50 | >50000±n/a nM |
|---|
| Citation |  Guerrero, M; Poddutoori, R; Urbano, M; Peng, X; Spicer, TP; Chase, PS; Hodder, PS; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist. Bioorg Med Chem Lett23:6346-9 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 2 |
|---|
| Name: | Sphingosine 1-phosphate receptor 2 |
|---|
| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 38883.16 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
|---|
| Residue: | 353 |
|---|
| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
|
|
|
|---|
| BDBM37340 |
|---|
| n/a |
|---|
| Name | BDBM37340 |
|---|
| Synonyms: | MLS000116372 | N,N-dicyclohexyl-5-propyl-1,2-oxazole-3-carboxamide | N,N-dicyclohexyl-5-propyl-3-isoxazolecarboxamide | N,N-dicyclohexyl-5-propyl-isoxazole-3-carboxamide | SMR000093349 | cid_5309153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H30N2O2 |
|---|
| Mol. Mass. | 318.4537 |
|---|
| SMILES | CCCc1cc(no1)C(=O)N(C1CCCCC1)C1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
