| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50496307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1296801 (CHEMBL3132626) |
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| Ki | 59±n/a nM |
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| Citation |  Nayak, A; Chandra, G; Hwang, I; Kim, K; Hou, X; Kim, HO; Sahu, PK; Roy, KK; Yoo, J; Lee, Y; Cui, M; Choi, S; Moss, SM; Phan, K; Gao, ZG; Ha, H; Jacobson, KA; Jeong, LS Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists. J Med Chem57:1344-54 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36643.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_479910 |
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| Residue: | 320 |
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| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
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| BDBM50496307 |
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| n/a |
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| Name | BDBM50496307 |
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| Synonyms: | CHEMBL3125717 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26BrN5O2 |
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| Mol. Mass. | 496.4 |
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| SMILES | [H][C@@]12C[C@]1([H])[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCc3cccc(Br)c3)nc(nc12)C#CCCCC |r| |
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| Structure | 
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