| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50045167 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_214387 |
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| IC50 | 68.0±n/a nM |
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| Citation |  Ogawa, H; Yamamura, Y; Miyamoto, H; Kondo, K; Yamashita, H; Nakaya, K; Chihara, T; Mori, T; Tominaga, M; Yabuuchi, Y Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihdyro-2(1H)-quinolinone. J Med Chem36:2011-7 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | Avpr1a | V1AR_RAT | VASOPRESSIN V1A | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47674.81 |
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| Organism: | RAT |
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| Description: | VASOPRESSIN V1A AVPR1A RAT::P30560 |
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| Residue: | 424 |
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| Sequence: | MSFPRGSQDRSVGNSSPWWPLTTEGSNGSQEAARLGEGDSPLGDVRNEELAKLEIAVLAV
IFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGP
DWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIATSWVLSFI
LSTPQYFIFSVIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVAPVVVLGTCYGF
ICYHIWRNIRGKTASSRHSKGDKGSGEAVGPFHKGLLVTPCVSSVKSISRAKIRTVKMTF
VIVSAYILCWAPFFIVQMWSVWDENFIWTDSENPSITITALLASLNSCCNPWIYMFFSGH
LLQDCVQSFPCCHSMAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGMWKDSPKSSKSIRFI
PVST
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| BDBM50045167 |
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| n/a |
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| Name | BDBM50045167 |
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| Synonyms: | 1-{1-[4-(8-Amino-octyloxy)-benzoyl]-piperidin-4-yl}-3,4-dihydro-1H-quinolin-2-one | CHEMBL60905 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H39N3O3 |
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| Mol. Mass. | 477.6383 |
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| SMILES | NCCCCCCCCOc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12 |
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| Structure | 
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