Compile Data Set for Download or QSAR

Found 280 hits with Last Name = 'miyamoto' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35718 (benzazepine derivative, 20) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C25H23ClN2O3/c1-16-5-2-3-6-20(16)24(30)27-19-11-8-17(9-12-19)25(31)28-14-4-7-23(29)21-15-18(26)10-13-22(21)28/h2-3,5-6,8-13,15,23,29H,4,7,14H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35719 (benzazepine derivative, 21) Show SMILES COC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H25ClN2O3/c1-17-6-3-4-7-21(17)25(30)28-20-12-9-18(10-13-20)26(31)29-15-5-8-24(32-2)22-16-19(27)11-14-23(22)29/h3-4,6-7,9-14,16,24H,5,8,15H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35725 (benzazepine derivative, 34) Show SMILES COc1cc(ccc1NC(=O)c1ccccc1C)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H25ClN2O4/c1-16-6-3-4-7-19(16)25(31)28-21-11-9-17(14-24(21)33-2)26(32)29-13-5-8-23(30)20-15-18(27)10-12-22(20)29/h3-4,6-7,9-12,14-15,23,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35715 (benzazepine derivative, 13a) Show SMILES CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H26ClN3O2/c1-17-6-3-4-7-21(17)25(31)29-20-12-9-18(10-13-20)26(32)30-15-5-8-23(28-2)22-16-19(27)11-14-24(22)30/h3-4,6-7,9-14,16,23,28H,5,8,15H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35725 (benzazepine derivative, 34) Show SMILES COc1cc(ccc1NC(=O)c1ccccc1C)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H25ClN2O4/c1-16-6-3-4-7-19(16)25(31)28-21-11-9-17(14-24(21)33-2)26(32)29-13-5-8-23(30)20-15-18(27)10-12-22(20)29/h3-4,6-7,9-12,14-15,23,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35721 (benzazepine derivative, 30) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2N2O3/c1-15-5-2-3-6-18(15)24(31)28-17-9-10-19(21(27)14-17)25(32)29-12-4-7-23(30)20-13-16(26)8-11-22(20)29/h2-3,5-6,8-11,13-14,23,30H,4,7,12H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35720 (benzazepine derivative, 22) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(OCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClN2O3/c1-3-17-34-26-9-6-16-31(25-15-12-21(29)18-24(25)26)28(33)20-10-13-22(14-11-20)30-27(32)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,26H,1,6,9,16-17H2,2H3,(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052948 (CHEMBL324251 | N-{4-[5-(Carbamoylmethyl-methyl-ami...) Show SMILES CN(CC(N)=O)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C28H30N4O3/c1-19-8-3-4-9-22(19)27(34)30-21-15-13-20(14-16-21)28(35)32-17-7-12-24(31(2)18-26(29)33)23-10-5-6-11-25(23)32/h3-6,8-11,13-16,24H,7,12,17-18H2,1-2H3,(H2,29,33)(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052924 (2,4-Dichloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahy...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c2ccccc12 Show InChI InChI=1S/C26H25Cl2N3O2/c1-30(2)23-8-5-15-31(24-7-4-3-6-21(23)24)26(33)17-9-12-19(13-10-17)29-25(32)20-14-11-18(27)16-22(20)28/h3-4,6-7,9-14,16,23H,5,8,15H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35724 (benzazepine derivative, 33) Show SMILES COc1cc(NC(=O)c2ccccc2C)ccc1C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H25ClN2O4/c1-16-6-3-4-7-19(16)25(31)28-18-10-11-20(24(15-18)33-2)26(32)29-13-5-8-23(30)21-14-17(27)9-12-22(21)29/h3-4,6-7,9-12,14-15,23,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052925 (CHEMBL331098 | N-[4-(5-Dimethylamino-2,3,4,5-tetra...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3cccc(C)c3)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-8-6-9-21(18-19)26(31)28-22-15-13-20(14-16-22)27(32)30-17-7-12-24(29(2)3)23-10-4-5-11-25(23)30/h4-6,8-11,13-16,18,24H,7,12,17H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052930 (2-Methyl-N-[4-(5-methyl-2,3,4,5-tetrahydro-benzo[b...) Show SMILES CN1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C25H25N3O2/c1-18-8-3-4-9-21(18)24(29)26-20-14-12-19(13-15-20)25(30)28-17-7-16-27(2)22-10-5-6-11-23(22)28/h3-6,8-15H,7,16-17H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35718 (benzazepine derivative, 20) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C25H23ClN2O3/c1-16-5-2-3-6-20(16)24(30)27-19-11-8-17(9-12-19)25(31)28-14-4-7-23(29)21-15-18(26)10-13-22(21)28/h2-3,5-6,8-13,15,23,29H,4,7,14H2,1H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35716 (benzazepine derivative, 18) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(NCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H28ClN3O2/c1-3-16-30-25-9-6-17-32(26-15-12-21(29)18-24(25)26)28(34)20-10-13-22(14-11-20)31-27(33)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,25,30H,1,6,9,16-17H2,2H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052954 (2-Methyl-N-[4-(2,3,4,5-tetrahydro-benzo[b]azepine-...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C25H24N2O2/c1-18-8-2-4-11-22(18)24(28)26-21-15-13-20(14-16-21)25(29)27-17-7-6-10-19-9-3-5-12-23(19)27/h2-5,8-9,11-16H,6-7,10,17H2,1H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052922 (3,5-Dichloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahy...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)c2ccccc12 Show InChI InChI=1S/C26H25Cl2N3O2/c1-30(2)23-8-5-13-31(24-7-4-3-6-22(23)24)26(33)17-9-11-21(12-10-17)29-25(32)18-14-19(27)16-20(28)15-18/h3-4,6-7,9-12,14-16,23H,5,8,13H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052915 (2-Methyl-N-{4-[5-(methyl-propyl-amino)-2,3,4,5-tet...) Show SMILES CCCN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C29H33N3O2/c1-4-19-31(3)26-14-9-20-32(27-13-8-7-12-25(26)27)29(34)22-15-17-23(18-16-22)30-28(33)24-11-6-5-10-21(24)2/h5-8,10-13,15-18,26H,4,9,14,19-20H2,1-3H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052941 (2-Methyl-N-[4-(5-methylamino-2,3,4,5-tetrahydro-be...) Show SMILES CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C26H27N3O2/c1-18-8-3-4-9-21(18)25(30)28-20-15-13-19(14-16-20)26(31)29-17-7-11-23(27-2)22-10-5-6-12-24(22)29/h3-6,8-10,12-16,23,27H,7,11,17H2,1-2H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052912 (CHEMBL323802 | N-{4-[5-(Cyanomethyl-methyl-amino)-...) Show SMILES CN(CC#N)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C28H28N4O2/c1-20-8-3-4-9-23(20)27(33)30-22-15-13-21(14-16-22)28(34)32-18-7-12-25(31(2)19-17-29)24-10-5-6-11-26(24)32/h3-6,8-11,13-16,25H,7,12,18-19H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35711 (benzazepine derivative, 14) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C27H28ClN3O2/c1-18-7-4-5-8-22(18)26(32)29-21-13-10-19(11-14-21)27(33)31-16-6-9-24(30(2)3)23-17-20(28)12-15-25(23)31/h4-5,7-8,10-15,17,24H,6,9,16H2,1-3H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052900 (CHEMBL334225 | N-[4-(5-Dimethylamino-2,3,4,5-tetra...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3)cc2)c2ccccc12 Show InChI InChI=1S/C26H27N3O2/c1-28(2)23-13-8-18-29(24-12-7-6-11-22(23)24)26(31)20-14-16-21(17-15-20)27-25(30)19-9-4-3-5-10-19/h3-7,9-12,14-17,23H,8,13,18H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052929 (2-Chloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahydro-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3Cl)cc2)c2ccccc12 Show InChI InChI=1S/C26H26ClN3O2/c1-29(2)23-12-7-17-30(24-11-6-4-9-21(23)24)26(32)18-13-15-19(16-14-18)28-25(31)20-8-3-5-10-22(20)27/h3-6,8-11,13-16,23H,7,12,17H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052896 (2-Methyl-N-[4-(3,4,5,6-tetrahydro-2H-benzo[b]azoci...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCCc2ccccc12 Show InChI InChI=1S/C26H26N2O2/c1-19-9-4-6-12-23(19)25(29)27-22-16-14-21(15-17-22)26(30)28-18-8-2-3-10-20-11-5-7-13-24(20)28/h4-7,9,11-17H,2-3,8,10,18H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35722 (benzazepine derivative, 31) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1Cl)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C25H22Cl2N2O3/c1-15-5-2-3-6-18(15)24(31)28-21-10-8-16(13-20(21)27)25(32)29-12-4-7-23(30)19-14-17(26)9-11-22(19)29/h2-3,5-6,8-11,13-14,23,30H,4,7,12H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052910 (CHEMBL118271 | N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(O)c2ccccc12 Show InChI InChI=1S/C25H24N2O3/c1-17-7-2-3-8-20(17)24(29)26-19-14-12-18(13-15-19)25(30)27-16-6-11-23(28)21-9-4-5-10-22(21)27/h2-5,7-10,12-15,23,28H,6,11,16H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052898 ((Methyl-{1-[4-(2-methyl-benzoylamino)-benzoyl]-2,3...) Show SMILES CCOC(=O)CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C30H33N3O4/c1-4-37-28(34)20-32(3)26-14-9-19-33(27-13-8-7-12-25(26)27)30(36)22-15-17-23(18-16-22)31-29(35)24-11-6-5-10-21(24)2/h5-8,10-13,15-18,26H,4,9,14,19-20H2,1-3H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052909 (2-Chloro-N-[4-(2,3,4,5-tetrahydro-benzo[b]azepine-...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C24H21ClN2O2/c25-21-10-3-2-9-20(21)23(28)26-19-14-12-18(13-15-19)24(29)27-16-6-5-8-17-7-1-4-11-22(17)27/h1-4,7,9-15H,5-6,8,16H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052893 (CHEMBL118922 | N-[4-(5-Ethylamino-2,3,4,5-tetrahyd...) Show SMILES CCNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-3-28-24-12-8-18-30(25-13-7-6-11-23(24)25)27(32)20-14-16-21(17-15-20)29-26(31)22-10-5-4-9-19(22)2/h4-7,9-11,13-17,24,28H,3,8,12,18H2,1-2H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35722 (benzazepine derivative, 31) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1Cl)C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C25H22Cl2N2O3/c1-15-5-2-3-6-18(15)24(31)28-21-10-8-16(13-20(21)27)25(32)29-12-4-7-23(30)19-14-17(26)9-11-22(19)29/h2-3,5-6,8-11,13-14,23,30H,4,7,12H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052908 (CHEMBL420880 | N-[4-(5-Amino-2,3,4,5-tetrahydro-be...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(N)c2ccccc12 Show InChI InChI=1S/C25H25N3O2/c1-17-7-2-3-8-20(17)24(29)27-19-14-12-18(13-15-19)25(30)28-16-6-10-22(26)21-9-4-5-11-23(21)28/h2-5,7-9,11-15,22H,6,10,16,26H2,1H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35719 (benzazepine derivative, 21) Show SMILES COC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H25ClN2O3/c1-17-6-3-4-7-21(17)25(30)28-20-12-9-18(10-13-20)26(31)29-15-5-8-24(32-2)22-16-19(27)11-14-23(22)29/h3-4,6-7,9-14,16,24H,5,8,15H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35724 (benzazepine derivative, 33) Show SMILES COc1cc(NC(=O)c2ccccc2C)ccc1C(=O)N1CCCC(O)c2cc(Cl)ccc12 Show InChI InChI=1S/C26H25ClN2O4/c1-16-6-3-4-7-19(16)25(31)28-18-10-11-20(24(15-18)33-2)26(32)29-13-5-8-23(30)21-14-17(27)9-12-22(21)29/h3-4,6-7,9-12,14-15,23,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052902 (CHEMBL115853 | N-[4-(5-Dimethylamino-2,3,4,5-tetra...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccc(C)cc3)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-10-12-20(13-11-19)26(31)28-22-16-14-21(15-17-22)27(32)30-18-6-9-24(29(2)3)23-7-4-5-8-25(23)30/h4-5,7-8,10-17,24H,6,9,18H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM50052909 (2-Chloro-N-[4-(2,3,4,5-tetrahydro-benzo[b]azepine-...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C24H21ClN2O2/c25-21-10-3-2-9-20(21)23(28)26-19-14-12-18(13-15-19)24(29)27-16-6-5-8-17-7-1-4-11-22(17)27/h1-4,7,9-15H,5-6,8,16H2,(H,26,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liver				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35716 (benzazepine derivative, 18) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(NCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H28ClN3O2/c1-3-16-30-25-9-6-17-32(26-15-12-21(29)18-24(25)26)28(34)20-10-13-22(14-11-20)31-27(33)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,25,30H,1,6,9,16-17H2,2H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052955 (2-Methyl-N-[4-(5-propylamino-2,3,4,5-tetrahydro-be...) Show SMILES CCCNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C28H31N3O2/c1-3-18-29-25-12-8-19-31(26-13-7-6-11-24(25)26)28(33)21-14-16-22(17-15-21)30-27(32)23-10-5-4-9-20(23)2/h4-7,9-11,13-17,25,29H,3,8,12,18-19H2,1-2H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35720 (benzazepine derivative, 22) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(OCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClN2O3/c1-3-17-34-26-9-6-16-31(25-15-12-21(29)18-24(25)26)28(33)20-10-13-22(14-11-20)30-27(32)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,26H,1,6,9,16-17H2,2H3,(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM50052954 (2-Methyl-N-[4-(2,3,4,5-tetrahydro-benzo[b]azepine-...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12 Show InChI InChI=1S/C25H24N2O2/c1-18-8-2-4-11-22(18)24(28)26-21-15-13-20(14-16-21)25(29)27-17-7-6-10-19-9-3-5-12-23(19)27/h2-5,8-9,11-16H,6-7,10,17H2,1H3,(H,26,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liver				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052918 (CHEMBL118204 | {1-[4-(2-Methyl-benzoylamino)-benzo...) Show SMILES CC(=O)ON=C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 |w:4.3| Show InChI InChI=1S/C27H25N3O4/c1-18-8-3-4-9-22(18)26(32)28-21-15-13-20(14-16-21)27(33)30-17-7-11-24(29-34-19(2)31)23-10-5-6-12-25(23)30/h3-6,8-10,12-16H,7,11,17H2,1-2H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Compound was tested for its ability to displace [3H]-AVP from its specific binding sites in rat Kidney (AVP-V2 receptor).				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35712 (benzazepine derivative, 15) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2cc(Cl)ccc12 Show InChI InChI=1S/C27H28ClN3O2/c1-18-7-4-5-8-22(18)26(32)29-21-13-10-19(11-14-21)27(33)31-16-6-9-24(30(2)3)23-15-12-20(28)17-25(23)31/h4-5,7-8,10-15,17,24H,6,9,16H2,1-3H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35715 (benzazepine derivative, 13a) Show SMILES CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H26ClN3O2/c1-17-6-3-4-7-21(17)25(31)29-20-12-9-18(10-13-20)26(32)30-15-5-8-23(28-2)22-16-19(27)11-14-24(22)30/h3-4,6-7,9-14,16,23,28H,5,8,15H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM50045167 (1-{1-[4-(8-Amino-octyloxy)-benzoyl]-piperidin-4-yl...) Show SMILES NCCCCCCCCOc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12 Show InChI InChI=1S/C29H39N3O3/c30-19-7-3-1-2-4-8-22-35-26-14-11-24(12-15-26)29(34)31-20-17-25(18-21-31)32-27-10-6-5-9-23(27)13-16-28(32)33/h5-6,9-12,14-15,25H,1-4,7-8,13,16-22,30H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Ability to displace [3H]- Arginine Vasopressin (AVP) from its specific binding sites in rat liver (V1 receptor)				J Med Chem 36: 2011-7 (1993) BindingDB Entry DOI: 10.7270/Q2DZ07BC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052928 (CHEMBL333201 | N-[4-(2,3,4,5-Tetrahydro-benzo[b]az...) Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c27-23(19-10-2-1-3-11-19)25-21-15-13-20(14-16-21)24(28)26-17-7-6-9-18-8-4-5-12-22(18)26/h1-5,8,10-16H,6-7,9,17H2,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052904 (CHEMBL333597 | N-[4-(5-Dimethylamino-2,3,4,5-tetra...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3[N+]([O-])=O)cc2)c2ccccc12 Show InChI InChI=1S/C26H26N4O4/c1-28(2)22-12-7-17-29(23-10-5-3-8-20(22)23)26(32)18-13-15-19(16-14-18)27-25(31)21-9-4-6-11-24(21)30(33)34/h3-6,8-11,13-16,22H,7,12,17H2,1-2H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052946 (CHEMBL334082 | N-[4-(5-Dimethylamino-2,3,4,5-tetra...) Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(N(C)C)c2ccccc12 Show InChI InChI=1S/C27H29N3O3/c1-29(2)23-12-8-18-30(24-11-6-4-9-21(23)24)27(32)19-14-16-20(17-15-19)28-26(31)22-10-5-7-13-25(22)33-3/h4-7,9-11,13-17,23H,8,12,18H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM50052892 (3,5-Dichloro-N-[4-(3,4-dihydro-2H-quinoline-1-carb...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1ccc(cc1)C(=O)N1CCCc2ccccc12 Show InChI InChI=1S/C23H18Cl2N2O2/c24-18-12-17(13-19(25)14-18)22(28)26-20-9-7-16(8-10-20)23(29)27-11-3-5-15-4-1-2-6-21(15)27/h1-2,4,6-10,12-14H,3,5,11H2,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM50052928 (CHEMBL333201 | N-[4-(2,3,4,5-Tetrahydro-benzo[b]az...) Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c27-23(19-10-2-1-3-11-19)25-21-15-13-20(14-16-21)24(28)26-17-7-6-9-18-8-4-5-12-22(18)26/h1-5,8,10-16H,6-7,9,17H2,(H,25,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liver				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair

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