| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phospholipase A2, major isoenzyme |
|---|
| Ligand | BDBM50055367 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_156355 (CHEMBL761685) |
|---|
| IC50 | 3±n/a nM |
|---|
| Citation |  Draheim, SE; Bach, NJ; Dillard, RD; Berry, DR; Carlson, DG; Chirgadze, NY; Clawson, DK; Hartley, LW; Johnson, LM; Jones, ND; McKinney, ER; Mihelich, ED; Olkowski, JL; Schevitz, RW; Smith, AC; Snyder, DW; Sommers, CD; Wery, JP Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. J Med Chem39:5159-75 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phospholipase A2, major isoenzyme |
|---|
| Name: | Phospholipase A2, major isoenzyme |
|---|
| Synonyms: | Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 |
|---|
| Type: | Hydrolase; monomer or homodimer |
|---|
| Mol. Mass.: | 16279.83 |
|---|
| Organism: | Sus scrofa (pig) |
|---|
| Description: | Purchased from Sigma. |
|---|
| Residue: | 146 |
|---|
| Sequence: | MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPV
DELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNC
DRNAAICFSKAPYNKEHKNLDTKKYC
|
|
|
|---|
| BDBM50055367 |
|---|
| n/a |
|---|
| Name | BDBM50055367 |
|---|
| Synonyms: | CHEMBL345986 | [3-Aminooxalyl-1-(3-chloro-benzyl)-2-ethyl-1H-indol-4-yloxy]-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19ClN2O5 |
|---|
| Mol. Mass. | 414.839 |
|---|
| SMILES | CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
