| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Integrase |
|---|
| Ligand | BDBM50055689 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_90723 (CHEMBL701116) |
|---|
| IC50 | 127000±n/a nM |
|---|
| Citation |  Zhao, H; Neamati, N; Hong, H; Mazumder, A; Wang, S; Sunder, S; Milne, GW; Pommier, Y; Burke, TR Coumarin-based inhibitors of HIV integrase. J Med Chem40:242-9 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Integrase |
|---|
| Name: | Integrase |
|---|
| Synonyms: | Human immunodeficiency virus type 1 integrase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32231.48 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | ChEMBL_90865 |
|---|
| Residue: | 288 |
|---|
| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
|
|
|
|---|
| BDBM50055689 |
|---|
| n/a |
|---|
| Name | BDBM50055689 |
|---|
| Synonyms: | 12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxatetraphen-11-one (Compound 13) | 7-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-7H-chromeno[4,3-b]chromen-6-one | CHEMBL32926 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H14O6 |
|---|
| Mol. Mass. | 410.3751 |
|---|
| SMILES | Oc1c(C2c3ccccc3Oc3c2c(=O)oc2ccccc32)c(=O)oc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
