| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50055715 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90724 (CHEMBL701117) |
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| IC50 | 110000±n/a nM |
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| Citation |  Zhao, H; Neamati, N; Hong, H; Mazumder, A; Wang, S; Sunder, S; Milne, GW; Pommier, Y; Burke, TR Coumarin-based inhibitors of HIV integrase. J Med Chem40:242-9 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50055715 |
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| n/a |
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| Name | BDBM50055715 |
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| Synonyms: | 4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thienyl)methyl]-2H-2-chromenone | CHEMBL235961 | CHEMBL82228 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H14O6S |
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| Mol. Mass. | 418.419 |
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| SMILES | Oc1c(C(c2cccs2)c2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12 |
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| Structure | 
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